| 急性一氧化碳中毒后迟发性脑病与自由基关系的初步研究 |
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| 引用本文： | 顾仁骏,吕路线,张秀明,尹景岗,宋景贵,郭素琴,郭云.急性一氧化碳中毒后迟发性脑病与自由基关系的初步研究[J].中国神经免疫学和神经病学杂志,1996(3). |
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| 作者姓名： | 顾仁骏 吕路线 张秀明 尹景岗 宋景贵 郭素琴 郭云 |
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| 作者单位： | 河南省精神病医院，中山医科大学，新乡市职业病防治研究所 |
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| 摘 要： | 测定了３１例急性一氧化碳中毒后迟发性脑病患者血清过氧化脂质（ＬＰＯ）、水溶性脂质过氧化物（ＷＳＦＳ）、谷胱甘肽过氧化物酶（ＧＰＸ）、维生素Ｅ（ＶＥ）的含量，并与健康者作了比较。结果表明，患者血清中ＬＰＯ、ＷＳＦＳ含量明显增高，ＧＰＸ、ＶＥ含量明显降低，与对照组比较有显著性差异。患者组治疗１个月后复查，结果上述指标均有不同程度改变，且与病情变化基本一致。提示自由基可能在本病发病中起重要作用。
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| 关 键 词： | 一氧化碳中毒，迟发脑病，自由基 |
The Primary Study of the Relationship between Encephalopathy after Acute Carbon Monoxide Poisoning and Free Radical |
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| Gu Renjun,Lu Luxian,Zhang Xiuming,Yin Jinggang, Song Jinggui,et al.The Primary Study of the Relationship between Encephalopathy after Acute Carbon Monoxide Poisoning and Free Radical[J].Chinese Journal of Neuroimmunology and Neurology,1996(3). |
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| Authors: | Gu Renjun Lu Luxian Zhang Xiuming Yin Jinggang Song Jinggui |
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| Abstract: | The levels of serum lipid peroxides(LPO),water-soluble fluorescence substance(WSFS),glutathione peroxidase(GPX)and vitamine E(VE)were studied on 31 patients with delayed encephalopathy after acute carbon monoxide poisoning(DEACMP).The results showed that LPO and WSFS were significantly higher,but GPX and VE were significantly lower in patients than that in controls,After treatment the patients were examined again,the LPO,WSFS,GPX and VE had similar change,It suggests that the free radical probably play an important part in producing of DEACMP. |
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| Keywords: | carbon monoxide poisoning delayed encephalopathy free radical |
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