肾移植前后未透析与透析效果及血液透析与腹膜透析的对比分析☆

背景：透析与肾移植都是治疗尿毒症的主要手段，由于肾源的不足，大部分尿毒症患者必须经过一段透析治疗来维持，等待接受移植肾源，虽然在透析期间患者能够得到较好状态，但近年来的未透析肾移植研究结果表明，移植前透析会对肾移植的效果有影响。 目的：利用CNKI数据库文献检索和深度分析功能，对肾移植和透析研究的文献资料趋势进行多层次探讨分析。 设计：文献计量学分析。 资料提取：以电子检索方式对CNKI数据库2002-01/2011-12有关肾移植和透析研究的文献进行分析，采用检索词为“肾移植(Renal transplantation)；透析(Dialysis)”，对检索的相关文献运用数据库中自带的分析功能和Excel软件绘制图表的功能进行分析，通过文字和图表的形式将统计和计量数据分析，描述其分布特征。 入选标准：纳入标准:①与肾移植相关的基础和临床研究论文。②与血液透析相关的基础和临床研究论文。③与腹膜透析相关的基础和临床研究论文。排除标准:①与文章目的无关的文献。②重复研究的文献。③刊社信息。④未发表的文献。⑤需电话追踪和手工检索逐一分析的文献。⑥年鉴。⑦护理内容的文献。 主要数据判定指标：以CNKI数据库学术期刊文献出版时间、文献数量、学科类别、研究机构、来源期刊、文献被引频次、文献下载频次、关联文献、作者分布、基金资助情况和主要关键词进行相关分析。并对肾移植前后未透析与透析研究进行对比分析，以及血液透析与腹膜透析的研究进行对比分析。 结果：在CNKI数据库学术期刊收录2002/2011的文献中，共检索到57篇与肾移植和透析研究相关的文献。文献数量产出趋于平稳状态，2004年和2008年文献产出数量最多；《中国组织工程研究与临床康复》杂志发表文献量为15篇，占全部文献的26.3%；透析研究以血液透析和腹膜透析的研究为主，还包括尿毒症患者生活质量的研究。选择肾移植还是透析治疗，需要综合考虑患者基本情况来选择最适合的肾替代治疗模式。 结论：通过文献计量学方法对CNKI数据库学术期刊关于肾移植和透析研究的文献进行分析，可为中国从事肾移植和透析基础研究和临床实施的医务工作者进一步确定科研思路提供有价值的参考。

Dialysis versus non-dialysis and hemodialysis versus peritoneal dialysis in renal transplantation

BACKGROUND: Dialysis and renal transplantation are the primary means of treatment of uremia. Due to insufficient renal sources, most of the uremic patients must be maintained after a dialysis treatment, waiting to accept renal sources. During dialysis, patients can get better, but in recent years, non-dialysis kidney transplant results show that transplantation before dialysis will have an impact on the effect of renal transplantation OBJECTIVE: Using CNKI database literature search and the depth of analysis capabilities, explore the multi-level analysis for the study of renal transplantation and dialysis of the literature data trends. DESIGN: Bibliometric data analysis. DATA RETRIEVAL: A search of related literature of renal transplantation and dialysis were performed in CNKI database using the key words of “renal transplantation, dialysis”, during 2002/1 to 2011/12. Using own database analysis capabilities and Excel charting functions to retrieve literature analysis, through the form of text and charts analysis the data , to describe its distribution characteristics. SELECTION CRITERIA: ①Basic and clinical research papers associated with renal transplantation.②Basic and clinical research papers associated with hemodialysis.③Basic and clinical research papers associated with peritoneal dialysis. Exclusion criteria:①Literature has nothing to do with the purpose of this review. ②Duplication of research literature. ③Journal's own information. ④Unpublished papers. ⑤The article need telephone follow up to analyze and manual searches. ⑥Yearbook.    ⑦The literature of nursing content。 MAIN OUTCOME MEASUREMENTS: In CNKI database, using academic journal articles published year, literature number, subject category, research institutions, source journals, literature citations, literature download frequency, associated literature, distribution of the author, distribution of the Funds and major key words to analysis. Comparative analysis between non-dialysis and dialysis effect before and after renal transplantation, hemodialysis and peritoneal dialysis was performed. RESULTS: The literature associated with academic journals in CNKI during 2002-2011, retrieved a total of 57 renal transplantation and dialysis research literature. The number of papers was gradually increasing. The most were published in 2004 and 2008. Journal of Clinical Rehabilitative Tissue engineering Research published 15 articles, accounting for 26.3% of all literature. The dialysis research was mainly based on hemodialysis and peritoneal dialysis, including the study of uremic patients quality of life. To choose kidney transplantation or dialysis treatment must be considered in patients with basic information to select the most appropriate mode of renal replacement therapy. CONCLUSION: Through the bibliometric data analysis based on CNKI database of academic journal literature of the renal transplantation and dialysis, to provide valuable reference for Chinese medical worker in renal transplantation and dialysis science basic research and clinical practice, to further define the thinking of scientific research.