聚甲基丙烯酸甲酯骨水泥与Cortoss骨水泥生物力学性能及聚合温度比较

背景：聚甲基丙烯酸甲酯骨水泥是其最常用的一种填充材料,但由于其存在聚合时放热、单体毒性等缺点,所以目前出现了以Cortoss为代表的生物新型骨水泥。目的：对比两种骨水泥在体外的力学性能。方法：将聚甲基丙烯酸甲酯与新型骨水泥Cortoss按照ISO5833:2002标准分别制作成抗压及抗弯模型,将制作的模型使用生物力学机测试两种骨水泥的抗弯及抗压模量,同时在制模过程中测量骨水泥聚合温度。结果与结论：与聚甲基丙烯酸甲酯骨水泥比较,Cortoss骨水泥在聚合过程中最高温度较低、抗压强度较强、抗弯模量降低,差异均有显著性意义(P < 0.05),而抗弯强度间差异无显著性意义(P > 0.05)。说明Cortoss生物力学强度优于聚甲基丙烯酸甲酯骨水泥,由于Cortoss在聚合时放热较少,所以其用于手术时有较好的安全性。 

Comparison of biomechanics property and exotherm between polymethylmethacrylate bone cement and Cortoss bone cement

BACKGROUND: Polymethylmethacrylate (PMMA) is a kind of bone cement commonly used for percutaneous kyphoplasty (PKP). However, it has inherent drawbacks, including a high curing exotherm and the incorporation of toxic components in their formulations. Now, there are some new biological bone cements, for example, Cortoss. OBJECTIVE: To compare the in vitro biomechanical properties of PMMA bone cement and Cortoss bone cement. METHODS: Both PMMA bone cement and Cortoss bone cement were used to make the anti-compression and anti-bending models according to ISO 5833:2002. Then, the compressive load strength and bending load strength were tested using mechanical testing machine. During the modeling process, the polymerization temperature was tested in their formulations.RESULTS AND CONCLUSION: The peak exotherm and bending modulus of Cortoss were significantly lower than those of PMMA, and the compressive strength was stronger than that of PMMA (P < 0.05). However, there was no significant difference in bending strength (P < 0.05 ). The biomechanical strength of Cortoss bone cement was better than that of PMMA bone cement. Due to its lower exotherm, Cortoss bone cement was safer during the operation.