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液体复苏对失血性休克所致肠道炎症反应及细菌移位的影响
引用本文:高新跃,吴长毅,庞庆丰,曾因明.液体复苏对失血性休克所致肠道炎症反应及细菌移位的影响[J].国际麻醉学与复苏杂志,2006,27(3):174-175,178.
作者姓名:高新跃  吴长毅  庞庆丰  曾因明
作者单位:1. 江苏省麻醉学研究所,江苏省麻醉学重点实验室,徐州市,221002;深圳市第四人民医院麻醉科,510180
2. 江苏省无锡市第四人民医院麻醉科,214062
3. 徐州医学院病理生理学教研室,221002
4. 江苏省麻醉学研究所,江苏省麻醉学重点实验室,徐州市,221002
摘    要:各种外伤导致的失血性休克,除了及时止血(如外科手术)外,还要强调液体复苏的重要性。以维持机体有效的循环血容量,保证重要脏器的血液灌注,恢复和保存重要脏器的功能。本文就不同液体复苏对失血性休克所致的肠道炎症反应及细菌移位的影响作一综述。1失血性休克所致的肠道炎症反应和细菌移位的可能机制1.1失血性休克所致的肠黏膜缺血缺氧机制在失血性休克的早期,由于血流再分布,使肠道内的血液灌注量明显减少,肠道组织细胞可能遭受缺血/缺氧损伤,如果持续时间长,缺血程度严重,可导致肠黏膜屏障功能障碍。肠黏膜细胞的线粒体功能首先受损,细胞…


Effects of different fluids resuscitation on the inflammation of lower intestine and bacterial translocation
GAO Xin-yue , WU Chang-yi ,PANG Qing-feng, et al.Effects of different fluids resuscitation on the inflammation of lower intestine and bacterial translocation[J].international journal of anesthesiology and resuscitation,2006,27(3):174-175,178.
Authors:GAO Xin-yue  WU Chang-yi  PANG Qing-feng  
Institution:The Key Lab of Anesthesiology of Jiangsu province,Anesthesiology Institute of Jiangsu Province, Xuzhou 221002, China
Abstract:The therapeutic strategies of hemorrhagic shock mainly include bleeding control and fluid resuscitation. However, current resuscitation fluids may further aggravate the inflammation of low intestine and bacterial translocation that causes organ dysfunction. This review discusses the possible mechanisms about the inflammation of lower intestine and bacterial translocation, and the effect of different fluids resuscitation on the inflammation of low intestine and bacterial translocation. However, it still has not perfectly fluid resuscitation used in hemorrhagic shock nowadays.
Keywords:fluid resuscitation  hemorrhagic shock  bacterial translocation  inflammation of low intestinel  intestinal barrier
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