| 抗神经降压素血清翻转刺激下丘脑弓状核引起的镇痛效应 |
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| 引用本文： | 谢俊霞,陈家津.抗神经降压素血清翻转刺激下丘脑弓状核引起的镇痛效应[J].青岛大学医学院学报,1988(3). |
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| 作者姓名： | 谢俊霞 陈家津 |
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| 作者单位： | 青岛医学院生理学教研室
(谢俊霞)，青岛医学院生理学教研室(陈家津) |
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| 摘 要： | 电刺激大鼠下丘脑弓状核具有明显的镇痛效应,侧脑室或下丘脑弓状核注射微量抗神经降压素血清可显著对抗这种效应。结果表明,下丘脑弓状核区的神经降压素参与刺激该区引起的镇痛作用。
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| 关 键 词： | 抗神经降压素 下丘脑 电刺激 止痛 大鼠 |
ANTI-NEUROTENSIN SERUM CAN REVERSE THE ANTINOCICEPTION INDUCED BY ELECTRICAL STIMULATION OF HYPOTHALAMIC ARCUATE NUCLEUS IN RATS |
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| Xie Junxia,Chen Jiajin.ANTI-NEUROTENSIN SERUM CAN REVERSE THE ANTINOCICEPTION INDUCED BY ELECTRICAL STIMULATION OF HYPOTHALAMIC ARCUATE NUCLEUS IN RATS[J].Acta Academiae Medicinae Qingdao Universitatis,1988(3). |
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| Authors: | Xie Junxia Chen Jiajin |
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| Institution: | Xie Junxia;Chen Jiajin Department of Physiology |
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| Abstract: | This study found that analgesic effect was produced by electrical
stimulation of hypothalamic arcuate nucleus (ARC) in rat. This analgesic
effect was antagonized by ventriculus lateralis cerebri or ARC microin-
jection of anti-neurotensin serum, but not by normal rabbit serum. These
results suggest that the antinociceptive effects induced by electrical
stimulation of ARC is mediated, at least partly, by neurotensin in the
rat. |
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| Keywords: | Anti-neurotensin Hypothalamus Electric stimulation Analgesia Rats |
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