| 2型糖尿病患者血清同型半胱氨酸浓度与糖化血红蛋白水平的关系 |
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| 引用本文： | 李莉萍,陈国超.2型糖尿病患者血清同型半胱氨酸浓度与糖化血红蛋白水平的关系[J].咸宁医学院学报,2009,23(6):473-475. |
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| 作者姓名： | 李莉萍 陈国超 |
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| 作者单位： | [1]长江大学医学院,湖北荆州434023 [2]武汉市武昌医院,湖北荆州434023 |
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| 摘 要： | 目的探讨2型糖尿病（T2DM）患者血清同型半胱氨酸（Hey）浓度与糖化血红蛋白水平的关系。方法以糖化血红蛋白平均值6．6％（糖尿病控制良好的评价标准）为临界，分为血糖控制良好组和血糖控制不良组，比较两组Hey浓度的差异，并分析两组Hcy浓度与糖化血红蛋白水平的相关性。结果Hcy值血糖控制良好组为（12．54±2．59）μmol／L，血糖控制不良组为（18．67±3．35）panol／L，两组比较，差异有显著性（P〈0．05）。血糖控制不良组两者相关系数0．823，血糖控制良好组两者相关系数0．568，Hey浓度与糖化血红蛋白水平呈正相关。结论监测血浆Hcy浓度，积极控制糖化血红蛋白水平，对预防或延缓糖尿病心血管并发症具有藿要素义．
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| 关 键 词： | 同型半胱氨酸 糖化血红蛋白 糖尿病 |
Research on the Relationship Between the Serum Homocysteine Level and HbA1c in Patients with Type 2 Diabetes |
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| LI Li-ping,CHEN Guo-chao.Research on the Relationship Between the Serum Homocysteine Level and HbA1c in Patients with Type 2 Diabetes[J].Journal of Xianning Medical College,2009,23(6):473-475. |
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| Authors: | LI Li-ping CHEN Guo-chao |
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| Institution: | LI Li-ping, CHEN Guo-chao ( Medical School of Yangtze University, Jinzhou Hubei 434023, China) |
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| Abstract: | Objective To explore the relationship between the serum homocysteine level and HbAlc in patients with type 2 diabetes. Methods According to good diabetic control evaluation criteria, the patients were was divided into good glycemic control group and poor glycemie control group. The contents of serum HbAle and homoeysteine were determined and the eorrelafion between HbA1 c and homoeysteine was analyzed. Results The homoeysteine level in good glyeemic control group was （12.54 ±2.59）μmol/L, while that of poor glycemic control group was （18.67 ＋3.35）μmol/L. There was significant difference between the two groups （P 〈 0.05）. Conclusion Homoeysteine concentration and HbAlc was positively correlated. Monitoring plasma homoeysteine levels and controling glycosylated hemoglobin level positively was of great significance. |
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| Keywords: | Hyperhomocysteinemia HbA1 c Diabetes |
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