| 家兔不同部位自体游离骨膜移植修复关节软骨缺损的实验比较 |
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| 引用本文： | 李亚伟,王伟民,霍建河,沈建农.家兔不同部位自体游离骨膜移植修复关节软骨缺损的实验比较[J].中国组织工程研究与临床康复,2004,8(2):366-367. |
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| 作者姓名： | 李亚伟 王伟民 霍建河 沈建农 |
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| 作者单位： | 洛阳市中心医院骨科,河南省洛阳市,471009 |
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| 摘 要： | 目的 探讨不同部位自体游离骨膜修复关节软骨缺损的能力.
方法 用大耳兔 32只,在股骨关节面造成 5 mm× 8 mm全层软骨缺损,分别行自体髂骨骨膜和胫骨骨膜游离移植术,术后
4及 8周取材做组织学观察比较. 结果 术后 8周自体髂骨骨膜移植侧、胫骨骨膜移植侧的优势组织性质分别为类透明软骨、幼稚软骨,前者形成软骨的质量优于后者.
结论 自体髂骨骨膜游离移植的成软骨能力优于自体胫骨骨膜,是较理想的自体骨膜游离移植取材部位
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| 关 键 词： | 关节软骨 缺损修复 自体骨膜移植 兔 |
Comparison the repair potential for cartilage defect in knee joints with different sourced free periosteal autografts in rabbits model |
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| Abstract.Comparison the repair potential for cartilage defect in knee joints with different sourced free periosteal autografts in rabbits model[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2004,8(2):366-367. |
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| Authors: | Abstract |
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| Abstract: | AIM:To investigate the repair potential for cartilage defect with different sourced free periosteal autografts in rabbits model.METHODS:A total of 32 rabbits with 5 mm× 8 mm full thickness of cartilage defects on femoral joint surface were used in this study,free iliac and tibia periosteal autografts were performed.Four and 8 weeks later,specimens were taken out for histological observation. RESULTS:Hyaline and premature cartilage dominated in the newly formed tissue after 8 weeks.The iliac periosteal autografts showed a better regeneration quality than those from tibia.CONCLUSION:Iliac free periosteal autografts possessed a stronger chondrogenesis potential than those of tibia,so iliac may be an optimal donor for free periosteal autografts. |
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