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急性心肌梗塞溶栓治疗对心室晚电位及室性心律失常的影响
引用本文:于左,王旭.急性心肌梗塞溶栓治疗对心室晚电位及室性心律失常的影响[J].中国危重病急救医学,1994,6(2):78-80.
作者姓名:于左  王旭
作者单位:青岛医学院附属医院心内科,青岛市市立医院内科
摘    要:比较了急性心肌梗塞溶栓治疗(溶栓组)和常规治疗(对照组)的心室晚电位及室性心律失常情况。结果:溶栓组心室晚电位发生率11.0%(5/46),显著低于对照组33.0/(18/55),P<0.05,时域参数中滤波后QRS时间和GRS未40ms的方报电压及频域分析中20~50H_z的振幅谱和能量谱面积比,溶栓组和对照组有显著差异(P<0.05),随访发现溶栓组猝死率(1/10.25%)低于对照组(5/46,11.0%)。结果提示:溶栓治疗使阻塞的冠脉再通,减少梗塞边缘区缺血,增强心电稳定性和传导性,使心肌梗塞后猝死率呈降低趋势。

关 键 词:溶栓治疗,心肌梗塞,心室晚电位

Effects of thrombolytic therapy in a cute myocardialinfarction on signal-averaged electroctrdiogram andventricular arrhythmias
YU ZUO,et al.Effects of thrombolytic therapy in a cute myocardialinfarction on signal-averaged electroctrdiogram andventricular arrhythmias[J].Chinese Critical Care Medicine,1994,6(2):78-80.
Authors:YU ZUO  
Abstract:The effects of intravenous thrombolysis on timedomain and frequency domain of signal-averagedelectrocardiogram (SAECG)and ventricular arrhy-thmia events were assessed in 1 01 patients with acutemyocardial infarction (AMI). 46 patients receivedintravenous urokinase(group A) and 55 receivedconventional medical treatment(group B).The inci-dence of ventricular late potentials of group A 11.0%(5/46) was significantly different from group B33.0%(18/55),P<0.05 Significant differences wereseen between group A and B in terms of filtered QRSduration,root-mean square voltage of the last40msec of the filtered QRS complex in time domainand amplitude area ratio,power area ratio in fre-quency domain(p<0.05).The follow-up studyshowed that the mortality of group A(2.5%,1/40)was lower than the group B(11.0%,5/46).Thefavorable effects of thromobolytic therapy was dueto patency of the infarct-related coronary artery andthe resultant amelioration of ischemia in the borderzone of the infarct which led to improvement of the electrical stability and conduction .
Keywords:thrombolytic therapy  myocardealinfarction  signal-averaged  venticular late poten-tials
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