早期运动对家兔跟腱断裂术后愈合的组织学影响

目的 动物实验的角度分析跟腱断裂术后早期运动与制动状态下组织学差异,为术后早期运动提供组织学证据.方法 将新西兰家兔随机分成正常组,早期运动组,石膏固定组.造模后对家兔跟腱进行组织学检查,寻找组织学差异.结果 家兔跟腱HE染色后,光镜下观察,早期运动组胶原纤维更粗（8.417±1.649）μm vs（6.818±1.025）μm,t=2.76,P＜0.05],排列更整齐,成纤维细胞更成熟;电镜下观察,早期运动组胶原原纤维的直径更大,差异有统计学意义（26.915±2.123）nm vs（21.725±3.768）nm,t=4.12,P＜0.01].结论 术后早期运动能够促进跟腱的组织学愈合.

The histological effects of early mobilization in the healing after achilles tendon of rabbits rupture repair

Objective To offer the histological proof of rabbits rupture repair after early mobilization.Method New zealand rabbits were random divided into 3 groups, including normal group, mobilization group (the experimental group) , and immobilization group.All rabbits' achilles tendons were inspected, and the histological difference were observed under light microscope and electron microscope respectively.Result The collagen fibers of the achilles tendons in the mobilization group under light microscope showed that it arrayed more regularly than in immobilization group.Fibroblasts were more maturate.The diameters of collagen fibrils under electron microscope in mobilization group were thicker(8.417 ± 1.649)μm vs (6.818 ± 1.025)μm, t = 2.76, P ＜ 0.05] than immobilization group.The results showed statistical significance(26.915 ±2.123)nm vs (21.725 ±3.768)nm, t =4.12, P ＜0.01].Conclusion Early mobilization after operation can promote the histological healing of achiles tendon.