Combination Therapy for Chronic Hepatitis B: Current Indications |
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| Authors: | Navin Paul Steven-Huy Han |
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| Affiliation: | (1) Department of Medicine/Division of Digestive Diseases, David Geffen School of Medicine at University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA;(2) Pfleger Liver Institute, David Geffen School of Medicine at University of California, Los Angeles, 200 UCLA Medical Plaza, Suite 214, Los Angeles, CA 90095, USA |
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| Abstract: | Hepatitis B infection remains a major public health problem globally and in the United States, with significant use of healthcare resources. Several therapeutic agents active against viral and host targets are currently available for its treatment. The success of combination therapy in HIV infection, which has similarities to hepatitis B in both therapeutic targets and treatment options, stimulated studies on the efficacy and safety of various combinations of available drugs in the treatment of hepatitis B infection. In this review, we analyze the current role of combination therapy in chronic hepatitis B infection. |
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