中国部分地区中老年人群骨质蔬松症流行病学研究

Theresearchisthelargesteffortonosteoporosisthathasbeenundertaken，andoneofthefewcountry－wideglobalefforts．TheresearchisespeciallyimportantwiththesuggestionthatChinesehavelowbonedensityingeneral，andtherapidagingoftheChinesepopulation犤１－２犦．１Materialsandmethods１．１SubjectsSubjectswereobtainedwithinformedconsentfrom５５９３HannationalityandregisteredinfiveareasofChinaincludingNorth，South－middle，East，South－westandNorth－eastbythestrati－fied－multi－steps－clustersamplingmethod…

Epeidemiological study on osteoporosis in middle-aged and elderly population in China

Objectives To understand the normal references of standardized bone mineral densit y(sBMD)in general population in China and investigate the distribution of prevalence rate and risk factories o f osteoporosis in the middle-aged and elderly population in China.Methods Using the three manufactures of Dual Energy X-ray Absorptiometry(DEXA)equipment,Bone mineral density(BMD)was measured among3521general population aged above 20years old in five area of China by the random sampling method;Questionnaires and BMD were surveyed from 5593people aged above 40years o ld in five administrative areas in China,by the stratified-multi-steps-cluster sampling method;216variables were analyzed by the non-c onditional logistic regression.Results We found out the standardized normal references of BMD and peak bone values in lumbar spine and proximal femur by sex and age;The total pre valence rate of osteoporosis in the p opulation aged over 60years old was 22.6%.Of them,the prevalence ra te of male was 15.0%and that of female was 28.6%(P <0.01);We screened 47risk factors that influence the osteoporosis includi ng the age ,the chronic disease in respiration,the stomach trouble and th e age of stop smoking which are common risk factors in male and femal e.Conclusions The prevalence rate of osteoporosis in females was higher than that of fem ale and in-creased with age.The prevention and treatment of osteoporosis are very i mportant to the female but should not be ignored in male;There are common influencing factors and there are some certain variances of the risk factors and exposed level in male a nd female in China.