| 耳针、中药对糖尿病大鼠CGRP、ET的影响 |
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| 引用本文： | 尚蓉,吕明庄,贺志光.耳针、中药对糖尿病大鼠CGRP、ET的影响[J].中国针灸,2001,21(9):15-23. |
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| 作者姓名： | 尚蓉 吕明庄 贺志光 |
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| 作者单位： | 贵阳医学院附属医院针灸科, |
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| 基金项目： | 贵州省卫生厅资助课题(G2000-18) |
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| 摘 要： | 目的：研究耳针，中药对糖尿病大鼠血浆降钙素基因相关肽（Calcitonin gene related peptide,CGRP)，内皮素（Endothelin,ET)等的影响。方法：利用链脲佐菌素（STZ）诱发的糖尿病大鼠接受耳针，中药治疗14周后，放免法测定血浆CGRP，ET等指标。结果：与正常组相比糖尿病大鼠血浆CGRP，ET水平明显升高，而耳针，中药治疗后明显降低。结论：耳针，中药防治糖尿病微血管病变的一种可能机制是良性调整血浆CGRP，ET水平。
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| 关 键 词： | 糖尿病 针灸疗法 耳针 降钙素基因相关肽 耳针疗效 内皮缩血管肽类 针灸效应 |
| 文章编号： | 0255-2930(2001)09-0555-03 |
| 修稿时间： | 2001年2月28日 |
Effects of Auricular Acupuncture and Chinese Medical Herbs on CGRP and ET Levels in Rats of Diabetes Mellitus |
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| Abstract: | Purpose To investigate effects of auricular acupuncture and Chinese medical herbs on calcitonin gene related peptide(CGRP)and endothelin(ET)levels in rats of diabetes mellitus.Methods After acupuncture and Chinese medical herbs were geven to streptozotocin induced diabetic rats for 14 weeks,and plasma CGRP and ET levels were determined with radioimmunoassay.Results CGRP and ET levels increased significantly in the diabetic rats as compared with control rats.After treatment with auricular acupuncture and Chinese medical herbs the levels of CGRP and ET were significantly reduced.Conclusion The favorable regulation of plasma CGRP and ET is possibly one of mechanisms for auricular acupuncture and Chinese midical herbs preventing and treating diabetic microangiopathy. |
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| Keywords: | Diabetes Mellitus/acup ther Auricular Acupuncture Calcitonin Gene related Peptide/auri acup eff Endothelins/acup eff |
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