Mitochondrial dysfunction and Huntington disease |
| |
| Authors: | Zhang Wei-Yan Gu Zhen-Lun Liang Zhong-Qin Qin Zheng-Hong |
| |
| Affiliation: | SooChow University School of Life Sciences; Department of Pharmacology, Soochow University School of Medicine, Suzhou 215123, China; E-mail: zhqin5@hotmail.com. |
| |
| Abstract: | Huntington disease (HD) is a chronic autosomal-dominant neurodegenerative disease. The gene coding Huntingtin has been identified, but the pathogenic mechanisms of the disease are still not fully understood. This paper reviews the involvement of mitochondrial dysfunction in pathogenesis of HD. |
| |
| Keywords: | mitochondrial dysfunction Huntington disease Huntingtin |
| 本文献已被 维普 万方数据 PubMed 等数据库收录！ |
