| 反相离子对高效液相色谱分析厚朴类原植物中季铵生物碱 |
| |
| 引用本文： | 崔建芳,章观德,宋万志. 反相离子对高效液相色谱分析厚朴类原植物中季铵生物碱[J]. 药学学报, 1988, 23(5): 383-387 |
| |
| 作者姓名： | 崔建芳 章观德 宋万志 |
| |
| 作者单位： | 中国医学科学院药物研究所分析室 北京(崔建芳，章观德)，中国医学科学院药物研究所分析室 北京(宋万志) |
| |
| 摘 要： | 本文建立了厚朴类原植物中三种主要生物碱(厚朴碱、柳叶木兰花碱、武当木兰碱)的反相离子对高效液相色谱法。用Nucleosil C18固定相,0.003 mol/L辛烷磺酸钠—乙腈(74:26)为流动相。方法简便、灵敏,并用此法分析比较了木兰属、木莲属16种36个样品,为指导临床用药、资源开发利用提供了一定科学依据。
|
| 关 键 词： | 原朴 厚朴碱 柳叶木兰花碱 武当木兰碱 离子对高效液相色谱法 |
| 收稿时间： | 1987-03-25 |
REVERSED PHASE ION-PAIR HPLC DETERMINATION OF QUATERNARY AMMONIUM ALKALOIDS IN THE TRADITIONAL CHINESE DRUG HOU-PO(MAGNOLIA OFFICINALIS) |
| |
| JF Cui,GD Zhang and WZ Song. REVERSED PHASE ION-PAIR HPLC DETERMINATION OF QUATERNARY AMMONIUM ALKALOIDS IN THE TRADITIONAL CHINESE DRUG HOU-PO(MAGNOLIA OFFICINALIS)[J]. Acta pharmaceutica Sinica, 1988, 23(5): 383-387 |
| |
| Authors: | JF Cui GD Zhang WZ Song |
| |
| Abstract: | The reversed phase ion-pair HPLC method of determination of the three main quaternary ammonium alkaloids (magnocurarine, salicifoline and magnosprengerine)in Huo-po(Magnolia officinalis)has been developed, The Nucleosil C18 column and Na-octanesulfonate—CH3CN (74:26) at pH 3.45 as mobile phase were used. The effect of sorts of counter ions, composition of mobile phase and pH on the chromatographic process have been investigated. This method is s imple, rapid and has been widely applied to the analysis of various species and localities of raw material drugs. |
| |
| Keywords: | Magnolia officinalis Magnocurarine Salicifoline Magnosprengerine Ion-pair HPLC |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《药学学报》浏览原始摘要信息 |
|
点击此处可从《药学学报》下载全文 |
