用全身PET/CT寻找转移瘤患者的原发灶

目的:对不明原因转移瘤患者，探讨利用正电子发射计算机断层显像（positron emission tomography/computed tomography，PET/CT）寻找肿瘤原发灶的临床价值。方法:回顾性收集经病理学证实或影像学检查诊断为转移瘤的137例住院患者的临床及PET/CT成像资料，计算全身PET/CT显像对不明原因转移瘤患者肿瘤原发灶的检出率，分析不同部位转移瘤原发灶检出率间的差异。结果:确诊1例淋巴瘤患者被排除，18F-FDG PET/CT正确检出原发病灶89例，检出率为65.4%（89/136）。18F-FDG PET/CT对于淋巴结转移、骨转移、肝转移及脑转移瘤肿瘤原发灶检出率分别为63.2%（36/57）、60.0%（18/30）、86.7%（13/15）和57.1%（8/14）。结论:全身PET/CT显像在不明原因转移瘤寻找肿瘤原发灶方面具有重要临床应用价值。

Diagnostic value of 18 F - FDG PET/CT imaging in metastatic carcinoma of unknown pri-mary tumor

Objective:To explore the value of whole body PET/CT scan with (18)F-fluorodeoxy glucose (FDG) in the diagnosis of metastatic carcinoma of unknown primary origin (CUP).Methods:A retrospective study was performed in patients diagnosed of metastatic carcinoma with CUP.All patients were confirmed by pathology or diagnostic imaging examinations.The recruited patients were received whole body 18F-FDG PET-CT scan.Histopathological findings were used to determine the diagnostic value of 18F-FDG PET-CT.Results:Total of 136 patients were included in the study.The primary tumor site was accurately identified by 18F-FDG PET/CT in 89 patients (89/136，65.4%)．The detection rate of the primary tumor site for metastatic lymph node carcinoma，bone metastasis，liver metastasis and brain metastasis were 63.2%(36/57)，60%(18/30)，86.7%(13/15) and 57.1%(8/14) respectively.Conclusion:Whole body 18F-FDG PET/CT has important clinical value in detecting primary site of CUP．