营养干预对宫颈癌患者同步放化疗耐受性及生活质量的影响

目的:探讨营养干预对宫颈癌患者同步放化疗耐受性及生活质量(QOL)的影响。方法:将86例宫颈癌患者随机分为营养干预组和对照组，观察两组患者的放疗中断率、化疗完成次数及放疗剂量达40Gy时生活质量评分情况。结果:营养干预组的放疗中断率为2.3%（1/43），对照组为18.6%（8/43），P=0.03；营养干预组完成化疗周期数为4.0±0.98，对照组为3.3±1.28，P=0.005；放射剂量达40Gy时两组患者QOL评分的差异有统计学意义（P＜0.01）。结论:营养干预能有效提高宫颈癌患者同步放化疗的耐受性，提高其生活质量。

Effect of nutritional intervention on tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy

Objective:To investigate the effect of nutritional intervention on tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy.Methods:All 86 cervical cancer patients receiving concurrent chemoradiotherapy were randomly divided into the nutritional intervention group (n=43) and the control group (n=43).To observe the radiotherapy interruption rates and the completed chemotherapy cycles.The quality of life when patients received radiotherapy dosages to 40Gy were detected by EORTC QLQ-C30.Results:The radiotherapy interruption rates of the nutritional intervention group and the control group were 2.3%(1/43) and 18.6%(8/43),P=0.03.The completed chemotherapy cycles of the nutritional intervention group and the control group were 4.0±0.98 and 3.3±1.28,P=0.005.The quality of life when patients received radiotherapy dosages to 40Gy had significantly different scores between the two groups (P＜0.05).Conclusion:Nutritional intervention can effectively improve the tolerance and quality of life in cervical cancer patients receiving concurrent chemoradiotherapy．