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电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床疗效及影响因素
引用本文:王争君,孙战文.电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床疗效及影响因素[J].现代肿瘤医学,2015,0(19):2758-2760.
作者姓名:王争君  孙战文
作者单位:黄石市中心医院胸心外科,湖北 黄石 435000
基金项目:湖北省自然科学基金面上项目(编号:2012FFB02324)
摘    要:目的:探讨电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床效果,总结影响恶性胸腔积液的相关因素。方法:回顾性分析2011年1月至2013年1月87例恶性胸腔积液患者的临床资料。全部采用电视胸腔镜胸膜固定术治疗,观察其术后的临床效果,并分析影响中位生存时间的因素。结果:电视胸腔镜胸膜固定术治疗恶性胸腔积液的总有效率为63.2%。不良反应总发生率为9.1%。Karnfsky生活质量稳定以上的占97.7%。胸膜肥厚和包裹积液的总发生率为19.5%。肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水Glu水平均是电视胸腔镜胸膜固定术治疗恶性胸腔积液的主要影响因素(P<0.05)。结论:电视胸腔镜胸膜固定术治疗恶性胸腔积液临床效果确切,而肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水Glu水平是影响预后的相关因素。

关 键 词:恶性胸腔积液  胸腔镜胸膜固定术  临床效果  影响因素

Clinical efficacy and influencing factors of malignant pleural effusion paitents treated with VATS pleurodesed
Wang Zhengjun,Sun Zhanwen.Clinical efficacy and influencing factors of malignant pleural effusion paitents treated with VATS pleurodesed[J].Journal of Modern Oncology,2015,0(19):2758-2760.
Authors:Wang Zhengjun  Sun Zhanwen
Institution:Department of Cardiothoracic Surgery,Central Hospital of Huangshi City,Hubei Huangshi 435000,China.
Abstract:Objective:To study the clinical efficacy and influencing factors of malignant pleural effusion paitents tredted with VATS pleurodesed.Methods:All 87 paitents with VATS pleurodesed from January 2011 to January 2013.Clinical data were analysed.They were treated by adopt video-assisted thoracoscope pleurodesis.Results:Clinical effect was 63.2%.Total incidence of adverse reaction was 9.1%.Karnfsky life quality stability was 97.7%.Pleural effusion hypertrophy and package the total incidence rate was 19.5%.Tumor types,CEA,LDH,protein content,ShaPeiLin perfusion,chest water Glu levels were video-assisted thoracoscope pleurodesis treatment of malignant pleural effusion main influenced factors (P<0.05).Conclusion:Video-assisted thoracoscope pleurodesis in the treatment of malignant pleural effusion is effective,and the tumor types,CEA,LDH,protein content,ShaPeiLin perfusion,chest water Glu levels are related factors affecting the prognosis.
Keywords:malignant pleural effusion  thoracoscope pleurodesis  clinical effect  influence factors
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