电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床疗效及影响因素

目的:探讨电视胸腔镜胸膜固定术治疗恶性胸腔积液的临床效果，总结影响恶性胸腔积液的相关因素。方法:回顾性分析2011年1月至2013年1月87例恶性胸腔积液患者的临床资料。全部采用电视胸腔镜胸膜固定术治疗，观察其术后的临床效果，并分析影响中位生存时间的因素。结果:电视胸腔镜胸膜固定术治疗恶性胸腔积液的总有效率为63.2%。不良反应总发生率为9.1%。Karnfsky生活质量稳定以上的占97.7%。胸膜肥厚和包裹积液的总发生率为19.5%。肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水Glu水平均是电视胸腔镜胸膜固定术治疗恶性胸腔积液的主要影响因素（P<0.05）。结论:电视胸腔镜胸膜固定术治疗恶性胸腔积液临床效果确切，而肿瘤类型、CEA、LDH、蛋白质含量、沙培林灌注、胸水Glu水平是影响预后的相关因素。

Clinical efficacy and influencing factors of malignant pleural effusion paitents treated with VATS pleurodesed

Objective:To study the clinical efficacy and influencing factors of malignant pleural effusion paitents tredted with VATS pleurodesed.Methods:All 87 paitents with VATS pleurodesed from January 2011 to January 2013.Clinical data were analysed.They were treated by adopt video-assisted thoracoscope pleurodesis.Results:Clinical effect was 63.2%.Total incidence of adverse reaction was 9.1%.Karnfsky life quality stability was 97.7%.Pleural effusion hypertrophy and package the total incidence rate was 19.5%.Tumor types，CEA，LDH，protein content，ShaPeiLin perfusion，chest water Glu levels were video-assisted thoracoscope pleurodesis treatment of malignant pleural effusion main influenced factors (P<0.05).Conclusion:Video-assisted thoracoscope pleurodesis in the treatment of malignant pleural effusion is effective，and the tumor types，CEA，LDH，protein content，ShaPeiLin perfusion，chest water Glu levels are related factors affecting the prognosis.