Effect of <Emphasis Type="Italic">Helicobacter bilis</Emphasis> Infection on Human Bile Duct Cancer Cells |
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Authors: | Satoru Takayama Hiroki Takahashi Yoichi Matsuo Yuji Okada Hiromitsu Takeyama |
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Institution: | (1) Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi Mizuho-cho Mizuho-ku, Nagoya 467-8601, Japan |
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Abstract: | Background
Helicobacter pylori infection is known to be associated with chronic atrophic gastritis, peptic ulcers, and gastric malignancies. However, the
effects of other Helicobacter species have not been investigated extensively. In mice, a close relationship is observed between Helicobacter hepaticus and hepatocellular carcinoma, and Helicobacter species can be found in humans, most commonly in extragastric organs. There have also been reports that H. bilis may be associated with biliary malignancies in humans. The effect of H. bilis infection on a human bile duct cancer cell line was investigated in this study. |
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Keywords: | |
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