| 糖尿病合并动脉粥样硬化血清抗人巨细胞病毒抗体检测 |
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| 引用本文： | 王凌燕,吴金义,张蕾,姜洋.糖尿病合并动脉粥样硬化血清抗人巨细胞病毒抗体检测[J].中国老年学杂志,2002,22(3):225-226. |
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| 作者姓名： | 王凌燕 吴金义 张蕾 姜洋 |
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| 作者单位： | 1. 吉林大学中日联谊医院心内科,吉林,长春,130031
2. 吉林省电力医院心内科 |
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| 摘 要： | 目的 明确巨细胞病毒感染与糖尿病动脉粥样硬化形成的关系。方法 用 ELISA方法检测了 56例糖尿病合并冠心病 (A组 )及48例未合并冠心病组的 (B组 )血清人巨细胞病毒 (HCMV) Ig G、 Ig M抗体。结果 A组患者 HCMV Ig G、 Ig M阳性率均明显高于 B组 ,而且 A组女性患者 HCMV感染率明显高于 B组女性患者。结论 HCMV可能在糖尿病患者 (尤其是女性患者 )动脉粥样硬化形成过程中发挥重要作用 ,CMV抗体阳性率有可能成为预测女性糖尿病患者发生大血管并发症的指标
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| 关 键 词： | 巨细胞病毒 糖尿病 动脉粥样硬化 |
| 文章编号： | 1005-9202(2002)03-0225-02 |
| 修稿时间： | 2001年10月9日 |
Cytomegalovirus Antibody was detected in Diabetic with Atherosclerosis |
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| WANG Ling yan,WU Jin yi,ZHANG Lei et al The Third Hospital of Jilin University,Jilin Changchun.Cytomegalovirus Antibody was detected in Diabetic with Atherosclerosis[J].Chinese Journal of Gerontology,2002,22(3):225-226. |
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| Authors: | WANG Ling yan WU Jin yi ZHANG Lei The Third Hospital of Jilin University Jilin Changchun |
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| Institution: | WANG Ling yan,WU Jin yi,ZHANG Lei et al The Third Hospital of Jilin University,Jilin Changchun 130021 |
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| Abstract: | Objective To discovere the association between human cytomegalovirus (HCMV) infection and atherosclerosis in diabetic. Methods Cytomegalovirus antibody level were detected by ELISA in diabetic with atherosclerosis (group A) and those without atherosclerosis (group B). Results Positive rate of HCMV IgG antibody in Group A was found obviously higher than that in group B. Furthermore, this find of difference is more significant in female patients. Conclusion s HCMV may play an important role in the acceletation of atherosclerosis in diabetic (especially female patients). Positive rate of HCMV antibody probably would be a good indication for the incidence of macrovascular complication in female diabetic patients. |
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| Keywords: | Cytomegalovirus Diabetes Mellitus Atherosclerosis |
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