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心舒康胶囊质量标准研究
引用本文:徐会平,高聪聪,徐鹏,常伟强,冯素香.心舒康胶囊质量标准研究[J].河南中医药学刊,2011(3):336-338.
作者姓名:徐会平  高聪聪  徐鹏  常伟强  冯素香
作者单位:[1]郑州大学,河南郑州450001 [2]河南中医学院,河南郑州450008
基金项目:河南省重大公益性科研项目(编号:081100912500)
摘    要:目的:建立心舒康胶囊质量控制标准。方法:采用薄层色谱(TLC)法对处方中葛根、川芎、丹参、赤芍进行了定性鉴别研究;采用反相高效液相色谱法对样品中的葛根素进行了含量测定。结果:TLC定性鉴别斑点清晰,灵敏度高,色谱特征明显,专属性强;含量测定葛根素的平均回收率为99.72%,RSD为1.49%(n=6)。结论:该法简便、准确、专属性强,可作为心舒康胶囊的质量控制方法。

关 键 词:心舒康胶囊  薄层色谱分析法  高效液相色谱法  葛根素  质量控制

Study on Quality Standard for Xinshukang Capsules
Xu Hui-ping,Gao Cong-cong,Xu Peng,Chang Wei-qiang,Feng Su-xiang.Study on Quality Standard for Xinshukang Capsules[J].Journal of Henan college of Traditional Chinese Medicine,2011(3):336-338.
Authors:Xu Hui-ping  Gao Cong-cong  Xu Peng  Chang Wei-qiang  Feng Su-xiang
Institution:2 Zhenzhou University,Zhengzhou,Henan,China 450001 Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008
Abstract:Objective:To establish the quality standard for Xinshukang Capsules.Methods:TLC was performed to Pueraria lobata,Ligusticum chuanxiong,Salvia miltiorrhiza and Paeonia lactiflora.HPLC was used to determine the content of puerarin.Results:TLC plates were clear without the interference of the blank control.The average recovery rates of puerarin were 99.72%,RSD=1.49%(n=6).Conclusion:The methods of identification and quantification were accurate,realizableand reproducible.It can be used effectively for the quality control of Xinshukang Capsules.
Keywords:Xinshukang Capsule  TLC  HPLC  puerarin  quality standard control
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