生脉注射液联合化疗对晚期非小细胞肺癌患者生活质量的影响

目的：观察生脉注射液联合化疗对晚期非小细胞肺癌患者生活质量的影响。方法：将60例晚期非小细胞肺癌按随机数字表法平均分成2组。对照组30例单纯应用化疗,28 d为1个疗程,根据病情缓解情况确定化疗疗程和时限。治疗组30例在对照组化疗基础上加用生脉注射液治疗,15 d为1疗程,2个疗程评价疗效。观察2组临床症状改善率、生活质量提高稳定率和毒副反应变化。结果：2组临床症状改善率比较,治疗组与对照组总改善率分别为83.3%和60.0%（P〈0.05）;2组生活质量提高稳定率比较,治疗组与对照组提高稳定率分别为70.0%和50.0%（P〈0.05）;2组毒副反应比较,治疗组毒副反应发生率明显低于对照组（P〈0.05）。结论：生脉注射液联合化疗治疗晚期非小细胞肺癌具有保护骨髓,改善临床症状,减轻毒副反应,提高生活质量,延长生存期等作用。

The Effect on Quality of life to Advanced Stage Non-small Cell Lung Cancer Patient Treated with Shengmai Injection Combined Chemotherapy

Objective ： To observe influence of the quality of life of the patients treated with sheng mai injection combination chemotherapy for advanced stage non-small cell lung cancer.Methods： 60 patients with terminal NSCLC were randomly divided into 2 groups.30 cases in pure chemotherapy,every 4 weeks for a cycle,according to the illness ease,determine the chemotherapy regimen and duration.30 cases in control group based on chemotherapy combined with shenmai injection treatment,15 days for 1 course of treatment,2 course of treatment efficacy evaluating.Observe 2 groups of clinical symptoms period,the quality of life,improve active and side-effect of change.Results： Total improving rate of 2 groups were 80.3%,60.0% respectively（P0.05）.2 groups of life quality improving active were 70.0% and 50.0%,respectively（P0.05）.Two groups of adverse reaction compare,adverse reaction rate the treatment group of obviously lower than in control group（P0.05）.Conclusion： Shengmai injection combination chemotherapy treating advanced non-small cell lung cancer with the protection of bone marrow can improve the clinical symptoms,reduce adverse reaction,improve life span and prolong surial functions.