云南省德宏州2005—2009年新报告HIV-1感染者中新近感染比例及其影响因素分析

目的 了解云南省德宏州2005-2009年新报告HIV-1感染者中新近感染者构成比及其影响因素.方法 对该州2005-2009年所有新报告HIV-1感染者的血清样本用BED HIV-1发病率捕获酶联法(BED-CEIA)检测以确定新近感染者.结果 2005-2009年德宏州共新报告HIV感染者9367例,对其中7252例(77.4%)进行BED-CEIA检测,其中954例(13.2%)为新近感染者,各年新报告HIV感染者中新近感染者所占比例依次是:2005年为11.21%、2006年为11.87%、2007年为17.55%、2008年为13.22%、2009年为12.22%.logistic多因素回归分析显示,在控制了各变量间的潜在混杂作用影响后,2009年度不同性别、不同年龄、不同户籍的HⅣ感染者中新近感染者所占比例显著不同,女性显著高于男性、11～19岁组显著高于50岁以上组、外地户籍(不含外籍)显著高于本地户籍、外籍(主要为缅甸籍)则显著低于本地户籍.结论 2005-2009年云南省德宏州新报告HIV感染者中HⅣ新近感染构成比呈历年小幅波动态势,其长期趋势尚有待进一步观察研究.2009年度不同社会人口学特征的新报告HIV感染者中新近感染所占比例显著不同.

Proportions and correlates of recent HIV infections among newly reported HIV/AIDS cases from 2005 through 2009 in Dehong prefecture, Yunnan province

Objective To determine the proportions and correlates of recent HIV infections among newly reported HIV/AIDS cases from 2005 through 2009 in Dehong prefecture, Yunnan province. Methods All available serum samples of newly reported HIV/AIDS cases during 2005-2009 period in Dehong prefecture, were tested using the BED HIV incidence capture enzyme immunoassay (BED-CEIA). Results A total of 9367 HIV/AIDS cases were newly reported in 2005through 2009, of whom 7252 (77.4%) were tested with BED-CEIA. Among the tested, 954 (13.2%)were positive for BED-CEIA and were regarded as recent HIV infections. The proportion of recent HIV infection among newly reported HIV/AIDS cases was 11.21% in 2005, 11.87% in 2006, 17.55%in 2007, 13.22% in 2008, and 12.22% in 2009. Multiple logistic regression analysis indicated that the proportion of recent HIV infections among newly reported HIV/AIDS cases in 2009 was significantly higher among females, those aged 11-19 years, and internal residents outside of Dehong prefecture,but significantly lower among immigrants who were mostly from Myanmar, than local residents.Conclusion From 2005 to 2009, the proportion of recent HIV infections among newly reported HIV/AIDS cases in Dehong prefecture in Yunnan province was fluctuating slightly. Future research is needed to examine its long-term and secular trend. Such proportion was significantly different by different sociodemographic characteristics.