| ghrelin与功能性消化不良 |
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| 引用本文： | 蔡顺天,王巍峰.ghrelin与功能性消化不良[J].胃肠病学和肝病学杂志,2011,20(6):579-582. |
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| 作者姓名： | 蔡顺天 王巍峰 |
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| 作者单位： | 1. 解放军总医院消化科,北京,100853;南开大学医学院
2. 解放军总医院消化科,北京,100853 |
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| 摘 要： | 功能性消化不良（FD）患者尽管未发现胃肠道器质性病变，但是研究提示FD可能存在胃动力、胃排空、胃十二指肠神经调节或内脏敏感性等胃肠道功能的改变。ghrelin作为主要由胃X／A样细胞产生的一种多肽，影响胃的动力、排空和分泌功能。最近的研究表明血清中的ghrelin水平与FD有一定的关系，提示其可能在FD的发病机制中起一定的作用，值得深入的研究。
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| 关 键 词： | ghrelin 功能性消化不良 餐后不适综合征 上腹部疼痛综合征 |
Ghrelin and functional dyspepsia |
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| CAI Shuntian,WANG Weifeng.Ghrelin and functional dyspepsia[J].Chinese Journal of Gastroenterology and Hepatology,2011,20(6):579-582. |
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| Authors: | CAI Shuntian WANG Weifeng |
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| Institution: | CAI Shuntian1,2,WANG Weifeng1,YANG Yunsheng1,21.Department of Gastroenterology,General Hospital of PLA,Beijing 100853,2.Medical College of Nankai University,China |
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| Abstract: | Though there are no evidences of organic change in patients with functional dyspepsia(FD),abnormalities of gastric emptying,dysregulation of gastroduodenal motility,and visceral hypersensitivity are often present in FD.Ghrelin is one kind of brain-gut peptide mainly secreted by gastric X/A-like cell.As it affects gastric motility,emptying and secretion,this peptide may play a pathophysiological role in FD.Recently,plasma ghrelin level is reported to be altered in FD,which indicates further investigations ar... |
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| Keywords: | ghrelin |
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