双能量CT肺动脉造影中Lung Vessels软件诊断肺动脉栓塞

目的 评价双能量CT肺动脉造影(DE-CTPA)中采用Lung Vessels软件诊断肺动脉栓塞(PE)的价值。方法 收集接受DE-CTPA扫描的可疑PE患者49例,采用Lung Vessels软件处理图像,记录病变血管的位置及数目,以CTPA结合临床作为诊断PE的金标准,按患者、段动脉及亚段动脉为单位计算Lung Vessels诊断PE的敏感度、特异度、阳性预测值及阴性预测值。结果 CTPA诊断PE患者29例,栓塞动脉共188支,包括段动脉138支,亚段动脉50支。分别以患者、段动脉及亚段动脉为单位,Lung Vessels诊断PE敏感度、特异度、阳性预测值、阴性预测值为96.55%(28/29)、45.00%(9/20)、71.79%(28/39)、90.00%(9/10),65.94%(91/138)、80.38%(598/744)、38.40%(91/237)、92.71%(598/645)和64.00%(32/50)、92.24%(1581/1714)、19.39%(32/165)、98.87%(1581/1599)。结论 DE-CTPA中采用Lung Vessels软件可直观显示肺血管,有助于提高对PE、尤其是段及亚段PE的诊断效能,具有潜在应用前景。

Lung Vessels software in diagnosis of pulmonary embolism in dual energy CT pulmonary angiography

Objective To evaluate the clinical value of Lung Vessels software in diagnosis of pulmonary embolism (PE) in dual energy CT pulmonary angiography (DE-CTPA). Methods Totally 49 patients of suspected PE underwent DE-CTPA. Lung Vessels software was used to process the images and the location and number of the abnormal vessel were recorded. The sensitivity, specificity, positive predictive value and negative predictive value of Lung Vessels were calculated with CTPA combined with clinic as gold standard based on patient, segment and sub-segment numbers. Results CTPA revealed 29 patients of PE with 188 diseased vessels, including 138 segments and 50 subsegments. The sensitivity, specificity, positive predictive value and negative predictive value of Lung Vessels in diagnosing PE was 96.55% (28/29), 45.00% (9/20), 71.79% (28/39), 90.00% (9/10) for patient as a unit, 65.94% (91/138), 80.38% (598/744), 38.40% (91/237), 92.71% (598/645) for segment as a unit and 64.00% (32/50), 92.24% (1581/1714), 19.39% (32/165), 98.87% (1581/1599) for subsegment as a unit, respectively. Conclusion In DE-CTPA, Lung Vessels software can directly show the lung vessels, which is helpful for diagnosing PE, especially segmental and subsegmental PE with potential application prospects.