肺癌纵隔淋巴结转移规律的分析

目的：探讨肺癌纵隔淋巴结转移的规律与特点。方法：对358例肺癌行肺切除加淋巴结廓清术，对其中132例N2肺癌病例的281组转移性纵隔淋巴结进行临床病理分析。结果：两组以上N2转移占62.1%，跳跃式转移占12.1%，左侧肺癌N2转移发生率较高的依次为5，7，6组淋巴结，右侧肺癌N2转移发生率较高的依次为4，7，3组淋巴结；瘤体越大N2转移发生率越高，肺癌分化程度越差，N2转移发生率越高，病理类型不同，N2转移发生率分别为，小细胞癌80.0%，腺癌45.1%，大细胞癌33.3%，鳞癌24.0%，结论：对N2肺癌行广泛，全面的纵隔淋巴结清扫是十分必要的。

Regulation of Mediastinal Lymph Nodes Metastasis in Patients with Lung Cancer

Objective:To investigate the rule and characteristics of mediastinal lymph nodes metastasis in lung cancer.Methods:358patients with lung cancer were performed pneu-monectomy and lymphadenectomy.Acquired281groups metastasis mediastinal lymph nodes were given clinicopathologic analysis in132cases N 2 lung cancer patients.Results:More than two groups N 2 metastasis was62.1%.Skipping metastasis was12.1%.The higher incidence rate of N 2 metasta sis in the left lung cancer decreased from fifth?seventh to sixth group lymph nodes,while it was from fourth?seventh to third group lymph nodes in the right lung cancer.The more volume,the lower differentiation of tumor,the higher incidence of N 2 metastasis.The incidence of N 2 metasta sis was different with different pathological type.The N 2 metastasis incidence of SCLC,adenocarcinoma,large cell lung cancer and squamous lung cancer was80.0%?45.1%?33.3%and24.0%re spectively.Conclusion:Exhaustive lymphadenectomy is necessary in N 2 lung cancer.