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中药化妆品中原料药的潜在毒副作用评析
引用本文:周伟璐,孔维军,杨美华,赵明,欧阳臻.中药化妆品中原料药的潜在毒副作用评析[J].中草药,2016,47(2):352-357.
作者姓名:周伟璐  孔维军  杨美华  赵明  欧阳臻
作者单位:中国医学科学院 北京协和医学院药用植物研究所, 北京 100193;江苏大学药学院, 江苏 镇江 212013;中国医学科学院 北京协和医学院药用植物研究所, 北京 100193;中国医学科学院 北京协和医学院药用植物研究所, 北京 100193;中国医学科学院 北京协和医学院药用植物研究所 海南分所, 海南 万宁 571533;江苏大学药学院, 江苏 镇江 212013;江苏大学药学院, 江苏 镇江 212013
基金项目:海南省重大科技项目“南药、黎药产业化关键技术研究”(ZDZX2013008)
摘    要:中药化妆品是由纯中药制成或在化学化合物基质中添加中药或中药有效成分的药物化妆品,因其以中医药理论为指导,绿色天然、安全可靠等特点正越来越为全世界消费者所喜爱,但并非天然的就是安全的。归纳并对化妆品中中药原料可能具有的毒副作用进行分类,如皮肤刺激性、光毒性以及积累毒性(肾毒性,肝毒性,神经毒性,致癌、致畸、致突变毒性,生殖毒性等)。以期为中药化妆品中的中药原料的正确使用提供参考,保证消费者的人身安全。

关 键 词:中药化妆品  中药原料  毒副作用  安全性  评析
收稿时间:2015/3/15 0:00:00

Assessment on potential toxic and side effects of raw materials in Chinese materia medica cosmetics
ZHOU Wei-lu,KONG Wei-jun,YANG Mei-hu,ZHAO Ming and OUYANG Zhen.Assessment on potential toxic and side effects of raw materials in Chinese materia medica cosmetics[J].Chinese Traditional and Herbal Drugs,2016,47(2):352-357.
Authors:ZHOU Wei-lu  KONG Wei-jun  YANG Mei-hu  ZHAO Ming and OUYANG Zhen
Institution:Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China;School of Pharmacy, Jiangsu University, Zhenjiang 212013, China;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China;Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China;Hainan Branch Institute of Medicinal Plant, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Wanning 571533, China;School of Pharmacy, Jiangsu University, Zhenjiang 212013, China;School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
Abstract:Chinese materia medica (CMM) cosmetics are made of natural CMM or by adding CMM or its active ingredients into the chemical compound matrices. They are increasingly favored by consumers all over the world due to the facts that they are guided by traditional Chinese medicine (TCM) theory, as well as are green, natural, safe, and reliable. But, not all natural CMM cosmetics are absolutely safe. This paper summarizes the toxic and side effects of some raw materials in CMM cosmetics, which are classified to skin-irritation, photo-toxicity, and the accumulation of toxic like renal toxicity, liver toxicity, neurotoxicity, and so on. This review will provide the references for the proper use of natural raw materials in CMM cosmetics to ensure the safety of consumers.
Keywords:Chinese materia medica cosmetics  raw materials of Chinese materia medica  toxic and side effects  safety  assessment
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