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Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants
Authors:Flatz-Jequier Aline  Posfay-Barbe Klara M  Pfister Riccardo E  Siegrist Claire-Anne
Institution:Department of Pediatrics, Children's Hospital, University Hospitals of Geneva and Medical Faculty of the University of Geneva, Geneva, Switzerland
Abstract:We evaluated the tolerance to immunization of 64 very low birth weight preterm infants. Thirty-three of the infants experienced a cardiorespiratory event after the first vaccination, and 6 of these 33 (18%) had a recurrence after the second vaccination, including 2 infants previously discharged to home. A cardiorespiratory event associated with the first vaccination was the sole risk factor for recurrence identified.
Keywords:BW  Birth weight  DTaP  Diphtheria-tetanus-acellular pertussis  DTwP  Diphtheria-tetanus-whole cell pertussis  ELBW  Extremely low birth weight  GA  Gestational age  VLBW  Very low birth weight  V1  First DTaP-based vaccination  V2  Second DTaP-based vaccination  V3  Third DTaP-based vaccination
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