| 流产、死胎患者男性因素初步分析 |
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| 引用本文： | 戴汝琳,王瑞雪,郑贤红,阮洋,刘睿智,邹积艳.流产、死胎患者男性因素初步分析[J].中国男科学杂志,2009,23(6):34-37. |
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| 作者姓名： | 戴汝琳 王瑞雪 郑贤红 阮洋 刘睿智 邹积艳 |
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| 作者单位： | 1. 吉林大学白求恩医学院细胞生物学教研室,吉林省生殖医学研究所,长春,130021
2. 吉林大学中日联谊医院妇产科 |
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| 摘 要： | 目的 分析探讨流产、死胎的男性因素.方法 利用精液常规分析、染色体核型分析、PCR技术和吖啶橙荧光染色方法,对102例不明原因自然流产1～3次或因死胎而人工流产患者的丈夫以及作为对照组的100例正常生育男性进行研究.结果 流产、死胎组精子密度、精子活率、精子(a+b)级活力和正常形态精子平均数低于正常生育对照组,有显著统计学差异(P＜0.001):流产、死胎组染色体核型异常率、Y染色体微缺失率和精子DNA完整率与正常对照组相比,差异有统计学意义(P＜0.05).结论 染色体核型异常、Y染色体微缺失和精子DNA损伤可能是导致流产、死胎原因.
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| 关 键 词： | 流产 自然/病因学 死胎/病因学 染色体畸变 |
Analysis of male factors on patients with abortion or fetal death |
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| Dai Rulin,Wang Ruixue,Zheng Xianhong,Ruan Yang,Liu Ruizhi,Zou Jiyan.Analysis of male factors on patients with abortion or fetal death[J].Chinese Journal of Andrology,2009,23(6):34-37. |
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| Authors: | Dai Rulin Wang Ruixue Zheng Xianhong Ruan Yang Liu Ruizhi Zou Jiyan |
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| Abstract: | Objective To investigate the male factors on patients with abortion or fetal death.Methods All semen samples were collected from 102 test men whose spouse had unexplained spontaneous abortion or artificial abortion due to fetal death and 100 normal men.Semen routine analysis,karyotype analysis,detection of Y chromosome deletion and DNA integrity were carried out in the study.Results The sperm density,sperm motility rate,sperm motility in grade(a+b) and proportion of normal morphological sperm in the abortio... |
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| Keywords: | abortion spontaneous/etiology fetal death male factors/etiology chromosome aberrations |
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