Renal immunoblastic sarcoma complicating immunosuppressive therapy for wegener granulomatosis |
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| Authors: | Grannum R Sant MD Angelo A Ucci Jr MD PHD Edwin M Meares Jr MD |
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| Institution: | From the Departments of Urology and Pathology, Tufts University School of Medicine and New England Medical Center Hospital, Boston, Massachusetts, USA |
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| Abstract: | A renal tumor developing in a patient receiving cyclophosphamide (Cytoxan) therapy for Wegener granulomatosis is reported. The tumor was similar histologically to the "immunoblastic" sarcoma that develops in renal allograft recipients as a complication of immunosuppressive therapy. This case report strengthens the cause and effect relationship between immunosuppressive drug usage and the subsequent development of neoplasia. |
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