Small-cell carcinoma of prostate |
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| Authors: | D P Sarma T G Weilbaecher |
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| Affiliation: | Department of Pathology, Veterans Administration Medical Center, New Orleans, Louisiana. |
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| Abstract: | Small-cell carcinoma of the prostate is rare, but lethal. We report on 2 cases and review another 6 cases reported in the English literature. Microscopically the tumor may be pure small-cell carcinoma like that seen in the lung or may have a mixed pattern of adenocarcinoma with small-cell carcinoma. This tumor most probably arises from the basal or reserve cells of the prostatic acini. The totipotential basal cells have dual capacity for differentiation into adenocarcinoma and small-cell carcinoma. |
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