左心耳电隔离在心房颤动治疗中的研究进展

近年来,多项研究证实左心耳与心房颤动的触发及维持密切相关,且左心耳电隔离(LAAEI)策略可有效改善房颤消融预后,减少房颤复发。目前主要通过射频或冷冻球囊导管消融、外科切除、经皮结扎左心耳等策略实现LAAEI,但加深对其并发症的认识很有必要,尤其是术后血栓事件与卒中的相关风险和预防。本文主要就左心耳的电生理特性、临床治疗进展及相关并发症做一综述。

Left atrial appendage electrical isolation in the treatment of atrial fibrillation: research progress

In recent years, several studies have demonstrated that the left atrial appendage is closely related to the induction and maintenance of atrial fibrillation, and the left atrial appendage electrical isolation (LAAEI) has been confirmed to effectively improve the success rate of atrial fibrillation ablation and reduce the recurrence of atrial fibrillation. Currently, LAAEI is mainly achieved through radiofrequency or cryoballoon ablation, surgical intervention, LARIAT ligation, etc. However, it is necessary to promote the understanding of its complications, especially the postoperative thrombus events and stroke. This paper reviews the anatomical characteristics of left atrial appendage, as well as the clinical treatment progress and related complications of LAAEI.