| 血清游离脂肪酸测定在2型糖尿病伴高血压患者中的应用 |
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| 引用本文： | 王凤清,徐美华,欧启水,陈良娟.血清游离脂肪酸测定在2型糖尿病伴高血压患者中的应用[J].福建医科大学学报,2010,44(6):450-452. |
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| 作者姓名： | 王凤清 徐美华 欧启水 陈良娟 |
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| 作者单位： | 福建医科大学,附属第一医院检验科,福州,350005 |
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| 摘 要： | 目的观察2型糖尿病和2型糖尿病伴高血压患者血清游离脂肪酸（FFA）的水平变化,探讨其与2型糖尿病高血压发展的关系。方法收集200例2型糖尿病（A组）和105例2型糖尿病伴高血压（B组）患者的血清,分别测定总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（TG）、游离脂肪酸（FFA）、脂蛋白aLP（a）]、血糖（GLU）、糖化血红蛋白（HbA1C）,并与健康对照组比较。结果 A、B组和对照组比较,FFA、LP（a）、GLU、TC、TG、LDL-C、ApoB、HbA1C的浓度明显高于对照组（P〈0.05或P〈0.01）,HDL-C、ApoA1的浓度明显低于对照组（P〈0.01）;与A组比较,B组仅有FFA的结果显著升高（P〈0.01）,HDL-C的浓度明显低于对照组（P〈0.05）。FFA与ApoB、GLU、TCH、TG、HbA1C呈正相关（P〈0.05或P〈0.01）。结论 FFA的结果在2型糖尿病伴高血压患者中显著升高,FFA升高与2型糖尿病伴高血压相关,可能在2型糖尿病高血压的发病过程中起重要作用。
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| 关 键 词： | 脂肪酸类 非酯化 糖尿病 2型 高血压 |
Application of Serum Free Fatty Acids in Patients with Type 2 Diatetes Mellitus Complicated with Hypertension |
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| WANG Fengqing,XU Meihua,OU Qishui,CHEN Liangjuan.Application of Serum Free Fatty Acids in Patients with Type 2 Diatetes Mellitus Complicated with Hypertension[J].Journal of Fujian Medical University,2010,44(6):450-452. |
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| Authors: | WANG Fengqing XU Meihua OU Qishui CHEN Liangjuan |
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| Institution: | WANG Fengqing,XU Meihua,OU Qishui,CHEN Liangjuan Department of Laboratory Medicine,The First Affliated Hospital,Fujian Medical University,Fuzhou,350005,China |
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| Abstract: | Objective To investigate the level of serum free fatty acids(FFA)in patients with type 2 diatetes mellitus(2-DM)complicated with hypertension,and explore its role in the pathogenesis of hypertension.Methods Two hundred 2-DM cases(A group)and 105 2-DM cases complicated with hypertension(B group) were collected.Total cholesterol(TC),Low-density lipoprotein cholesterol(LDL-C),Triglyceride(TG),Free fatty acid(FFA),Lipoprotein a(LP(a),Glucose(GLU) and glycosylated hemoglobin Alc(HbA1C) were measured in each grou... |
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| Keywords: | fatty acids Nonesterified hypertension diatetes mellitus type 2 |
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