| 多发性硬化的发作性症状 |
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| 引用本文： | 蔡兴秋,赵翁平.多发性硬化的发作性症状[J].中华神经科杂志,1996,29(1):26-28. |
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| 作者姓名： | 蔡兴秋 赵翁平 |
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| 作者单位： | 南京医科大学脑科医院 |
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| 摘 要： | ２６例伴有发作性症状的多发性硬化（ＭＳ），占同期ＭＳ住院患者的２１．５％（２６／１２１）。其中癫痫（１１例）和痛性强直（９例）是较常见的发作类型，而发作性复视、三叉神经痛、猝倒、发作性视力障碍、瘙痒及构音障碍等则相对少见。这些发作性症状的共同特点是症状突然发生，突然停止，持续时间短暂，呈刻板式反复发作，有的可以是ＭＳ的首发症状。可能的发病机理是由于中枢神经系统脱髓鞘损害，使神经轴索纤维间冲动发生横向扩散所致。卡马西平等抗痉药物多可控制发作。
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| 关 键 词： | 多发性硬化 发作性症状 癫痫 |
Paroxysmalsymptomsinmultiplesclerosis |
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| CaiXingqiu,ZhaoXiping,DengRongkun.Paroxysmalsymptomsinmultiplesclerosis[J].Chinese Journal of Neurology,1996,29(1):26-28. |
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| Authors: | CaiXingqiu ZhaoXiping DengRongkun |
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| Institution: | CaiXingqiu,ZhaoXiping,DengRongkun.DepartmentofNeurology,BrainHospitalofNanjingMedicalUniversity,Nanjing210029 |
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| Abstract: | Twenty-sixpatientswithparoxysmalsymptomsinmultiplesclerosis(MS)werere-ported.Theyconstituted21.48percentofour121admitedcasesofMS.Epilepsy(11cases)andpainfultonicspasm(9cases)werethemostcommontypesofatacks.Sometypesofatackssuchasparoxysmaldiplopia,trigeminalneuralgia,dropatacks,visiondisturbances,itchinganddysarthriawererelativelyrare.Thecommoncharacteristicsoftheseparoxysmalsymptomsconsistedofsuddenonset,shortdurationandrepetitiveandstereotypedpatern.In5patientstheseattacksweretheini-tialsymptomsofMS.ThepathogenicmechanismoftheparoxysmalsymptomsinMSprobablyisre-latedtoatransverselyspreadingimpulsesbyactivationoftheneuralaxonswithinthedemylinatinglesionintheCNS.ThesymptomscanbecontroledwithCarbamazepineorotherantiepileptics. |
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| Keywords: | MultiplesclerosisParoxysmalsymptomsEpilepsy |
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