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迷走神经刺激激活丘脑和下丘脑室旁核的谷氨酸能神经元的探讨
引用本文:唐敏峰,丁炯,张璐,李雷,韩群颖,TANG Min-feng,DING Jiong,ZHANG Lu,LI Lei,HAN Qun-ying.迷走神经刺激激活丘脑和下丘脑室旁核的谷氨酸能神经元的探讨[J].南京医科大学学报,2006,26(2):105-107,F0003.
作者姓名:唐敏峰  丁炯  张璐  李雷  韩群颖  TANG Min-feng  DING Jiong  ZHANG Lu  LI Lei  HAN Qun-ying
作者单位:南京医科大学人体解剖学系,江苏南京210029
基金项目:江苏省重点实验室基金;南京医科大学校科研和教改项目
摘    要:目的:研究迷走神经刺激(VNS)后激活的丘脑室旁核(PV)、下丘脑室旁核(PVN)的神经元是否含谷氨酸能神经元。方法:利用FOS和谷氨酸免疫组化双标法观察迷走神经刺激后PV、PVN的双标细胞。结果:VNS后PV、PVN中存在谷氨酸和FOS双标细胞。结论:VNS激活了PV、PVN的谷氨酸能神经元。

关 键 词:迷走神经刺激  谷氨酸  丘脑室旁核  下丘脑室旁核
文章编号:1007-4368(2006)02-0105-03
收稿时间:2005-05-08
修稿时间:2005-05-08

Activation of glutamatergic neurons in paraventricular nucleus of thalamus and hypothalamus due to vagus nerve stimulation
TANG Min-feng,DING Jiong,ZHANG Lu,LI Lei,HAN Qun-ying.Activation of glutamatergic neurons in paraventricular nucleus of thalamus and hypothalamus due to vagus nerve stimulation[J].Acta Universitatis Medicinalis Nanjing,2006,26(2):105-107,F0003.
Authors:TANG Min-feng  DING Jiong  ZHANG Lu  LI Lei  HAN Qun-ying
Institution:Department of Anatomy, NJMU, Nanjing 210029, China
Abstract:Objective: To investigate the glutamatergic neurons activity in paraventricular nucleus of thalamus (PV) and hypothalamus (PVN) after vagus nerve stimulation (VNS). Methods: Immunohistochemical double-labled technique was used to observe the double-labled cells in PV and PVN after VNS. Results: Glutamate/FOS double-labeled cells were found in PV and PVN after VNS. Conclusion: Glutamatergic neurons are activated in PV and PVN after VNS.
Keywords:FOS
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