| 奎硫平与利培酮治疗精神分裂症对照研究 |
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| 引用本文： | 杨吉坤,王小全,宗元生,贾敏. 奎硫平与利培酮治疗精神分裂症对照研究[J]. 临床精神医学杂志, 2003, 13(5): 300-301 |
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| 作者姓名： | 杨吉坤 王小全 宗元生 贾敏 |
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| 作者单位： | 1. 653100,云南玉溪市第二人民医院
2. 甘肃天水市精神病医院 |
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| 摘 要： | 目的：评价奎硫平与利培酮治疗精神分裂症阴性症状的临床疗效与安全性。方法：对64例首次住院的以阴性症状为主的精神分裂症患者，随机分为两组，分别选用奎硫平或利培酮进行8周治疗，采用阳性症状与阴性症状量表(PANSS)评定疗效，用副反应量表(TESS)评定不良反应。结果：两药对精神分裂症阴性症状疗效相当，不良反应发生率及严重程度均相仿。结论：奎硫平与利培酮对精神分裂症阴性症状均有肯定的疗效，且安全性较高。
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| 关 键 词： | 奎硫平 利培酮 精神分裂症 阴性症状 |
| 文章编号： | 1005-3220(2003)05-0300-02 |
| 修稿时间： | 2003-02-12 |
A comparative study between quetiapine and risperidone in the treatment of schizophrenia |
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| Yang Jikun,Wang Xiaoquan,Zhong Yuansheng,et al.. A comparative study between quetiapine and risperidone in the treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 2003, 13(5): 300-301 |
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| Authors: | Yang Jikun Wang Xiaoquan Zhong Yuansheng et al. |
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| Affiliation: | Yang Jikun,Wang Xiaoquan,Zhong Yuansheng,et al.The Second People's Hospital of Yuxi,Yunnan 653100 |
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| Abstract: | Objective:To compare the effect and safety between quetiapine and risperidone in the treatment of negative symptoms in schizophrenia. Method:Sixty four first admitted schizophrenic patients with negative symptoms and a course less than 5 years were randomly divided into two groups receiving quetiapine and risperidone respectively for 8 weeks.PANSS was used to evaluate the effect and TESS was used to evaluate the side effects. Results:Both groups had a similar effect,occurrence rate and severity of side effects. Conclusion:Quetiapine and risperidone had a definite effect in the treatment of negative symptoms in schizophrenia and had rather high safety. |
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| Keywords: | Quetiapine Risperidone Schizophrenia Negative symptom |
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