归脾合剂治疗功能性消化不良伴抑郁症的临床观察

目的观察养心安神方药治疗功能性消化不良伴抑郁症的临床疗效。方法选择120例中医辨证属心脾两虚,西医诊断功能性消化不良伴抑郁症者为观察对象,按照临床症状积分法配对分为A组(吗丁啉治疗)、B组(归脾合剂治疗)、C组(归脾合剂 吗丁啉治疗)各40例,疗程均为8周;并通过等级评判法和汉密顿焦虑量表(HAMA)测定法,观察三组治疗前后症状变化。结果治疗8周后消化道症状改善的总有效率,C组为87.5%,B组为85.0%,均明显高于A组的57.5%,(P<0.01,P<0.05);C组和B组间虽无明显差异(P>0.05),但两组显效率存在明显差异(P<0.05)。治疗前后HAMA总均分比较,A组无明显变化(P>0.05),B组和C组均有良好效果(P<0.01)。结论归脾合剂能有效改善功能性消化不良伴有的抑郁症表现;与吗叮啉合用能使临床疗效更明显。

Clinical Observation of "Guipi Mixture" in Treating Functional Dyspepsia with Depression

Objective To observe the clinical effects of "Guipi Mixture" in the treatment of functional dyspepsia with depression.Methods 120 subjects were randomized into three groups:group A in which 40 cases were treated with Motilium,group B in which 40 cases were treated with "Guipi Mixture" and group C in which 40 cases were treated with "Guipi Mixture" and Motilium,with a course of 8 weeks.Results The total effective rate was 87.5% in group C and 85.0% in group B,higher than 57.5% in group A(P< 0.05) .Conclusion "Guipi Mixture" can effectively improve functional dyspepsia with depression.