| 尿中83—1除草剂代谢产物的鉴定 |
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| 引用本文： | 罗永义,喻凯.尿中83—1除草剂代谢产物的鉴定[J].中国卫生检验杂志,1994,4(2):70-72. |
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| 作者姓名： | 罗永义 喻凯 |
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| 作者单位： | 华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学公共卫生学院，华西医科大学仪器中心，华西医科大学公共卫生学院 四川成都 610041，四川成都 610041，四川成都 610041，四川成都 610041，四川成都 610041 |
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| 基金项目： | 国家教委博士点基金资助项目 |
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| 摘 要： | 本文采用高效液相色谱、质增、紫外和红外光谱对经83—1除草剂(2,4—二氯—6—硝基酚铵)染毒后大鼠尿液中出现的5种组分的化学结构进行了鉴定,并用纯品对照进行确证,发现组分Ⅴ为未代谢的农药母体,其余4种为代谢产物,依次为:二氯氨基酚、二氯氨基酚丙酮酸结合物、二氯羟氨基酚缩合物和二氯氨基酚葡萄糖醛酸结合物。
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| 关 键 词： | 尿 2 4—二氯—6—硝基酚铵 2 4—二氯—6—氨基酚 生物监测 |
Identification of the Metabolites of Ammonium Salt,2,4-dichloro-6-nitrophenol in Urine |
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| Luo Yongyi Yu Kai Zhang Kerong Sun Manling Sun Aiming Xong Ying College of Public health,West China University of Medical Sciences.Identification of the Metabolites of Ammonium Salt,2,4-dichloro-6-nitrophenol in Urine[J].Chinses Journal of Health Laboratory Technology,1994,4(2):70-72. |
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| Authors: | Luo Yongyi Yu Kai Zhang Kerong Sun Manling Sun Aiming Xong Ying College of Public health West China University of Medical Sciences |
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| Abstract: | The structure of the five new components in the urine of rats which had been exposed to ammonium salt. 2,4-dichloro- 6- nitrophenol was identified by high-performance liquid chromatography, mass spertrometry, ultra - violet and infrared spectrometry. It was found that the component No. V was the original herbi cide, and the others were its metabolites, they were 2,4 -dichioro -6-aminophenol(DCAP),a-
eylate of DCAP and propanonic acid, polymer of 2, 4 -diehloto - 6 - hydroxyiaminophenol and 2,4-dichloro-6-aminophenolglucocidic acid, respectively. |
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| Keywords: | Urine Ammonium salt 2 4 - dichloro - 6 -nitrophenol2 4-dichloro-6-aminophenolBlological monitory |
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