| 用M-NRTL模型及平衡空气法交叉验证甘氨酸溶液的渗透压 |
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| 引用本文： | 谭晓莹,詹婷婷,詹先成,王晓兰,徐敖,付茜,李成容. 用M-NRTL模型及平衡空气法交叉验证甘氨酸溶液的渗透压[J]. 华西药学杂志, 2015, 30(2): 165-166 |
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| 作者姓名： | 谭晓莹 詹婷婷 詹先成 王晓兰 徐敖 付茜 李成容 |
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| 作者单位： | 1. 四川大学华西药学院 靶向药物与释药系统教育部重点实验室,四川成都,610041
2. Division of Biostatistics, Dept.of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA |
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| 基金项目： | 国家自然科学基金资助项目(批准号:81273444) |
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| 摘 要： | 目的尝试通过药物溶液的浓度计算其渗透压。方法采用M-NRTL模型,由甘氨酸溶液浓度计算其渗透压,并应用平衡空气法测定溶液的渗透压。结果应用双向单侧t检验法和多重检验调整法进行验证,结果显示M-NRTL模型的计算值与平衡空气法的测定值具有等效性。结论可以应用物理模型由药物溶液的浓度计算渗透压值。
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| 关 键 词： | 渗透压 活度系数 M-NRTL模型 平衡空气法 甘氨酸 |
Cross-validating the osmotic pressure based on modified NRTL model with air humidity osmometry over the whole concentration of glycine solutions |
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| TAN Xiao-ying,ZHAN Ting-ting,ZHAN Xian-cheng,WANG Xiao-lan,XU Ao,FU Qian,LI Cheng-rong. Cross-validating the osmotic pressure based on modified NRTL model with air humidity osmometry over the whole concentration of glycine solutions[J]. West China Journal of Pharmaceutical Sciences, 2015, 30(2): 165-166 |
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| Authors: | TAN Xiao-ying ZHAN Ting-ting ZHAN Xian-cheng WANG Xiao-lan XU Ao FU Qian LI Cheng-rong |
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| Affiliation: | TAN Xiao-ying;ZHAN Ting-ting;ZHAN Xian-cheng;WANG Xiao-lan;XU Ao;FU Qian;LI Cheng -rong;Key Laboratory of Drug Targeting,West China School of Pharmacy,Sichuan University;Division of Biostatistics,Dept. of Pharmacology and Experimental Therapeutics,Thomas Jefferson University; |
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| Abstract: | |
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| Keywords: | Osmotic pressure Activity coefficient Modified NRTL model Air humidity osmometry Glycine |
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