Invasive group B streptococcal infections in Finland: a population-based study |
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Authors: | Lyytikäinen Outi Nuorti J Pekka Halmesmäki Erja Carlson Petteri Uotila Jukka Vuento Risto Ranta Tapio Sarkkinen Hannu Ammälä Martti Kostiala Anja Järvenpää Anna-Liisa |
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Institution: | *National Public Health Institute, Helsinki, Finland;†Helsinki University Central Hospital, Helsinki, Finland;‡Tampere University Hospital, Tampere, Finland;§Päijät-Häme Central Hospital, Lahti, Finland;¶Jorvi Hospital, Espoo, Finland |
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Abstract: | We analyzed surveillance data on group B streptococcus (GBS) infection in Finland from 1995 to 2000 and reviewed neonatal cases of early-onset GBS infection in selected hospitals in 1999 to 2000. From 1995 to 2000, 853 cases were reported (annual incidence 2.2-3.0/100,000 population). We found 32-38 neonatal cases of early-onset GBS disease per year (annual incidence 0.6-0.7/1,000 live births). In five hospitals, 35% of 26 neonatal cases of early-onset GBS infection had at least one risk factor: prolonged rupture of membranes, preterm delivery, or intrapartum fever. Five of eight mothers screened for GBS were colonized. In one case, disease developed despite intrapartum chemoprophylaxis. Although the incidence of early-onset GBS disease in Finland is relatively low, some geographic variation exists, and current prevention practices are suboptimal. Establishing national guidelines to prevent perinatal GBS is likely to reduce the incidence of the disease. |
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Keywords: | Group B streptococcus invasive bacterial infection epidemiology population-based study early-onset neonatal disease prevention research |
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