Function-preserving surgery for breast cancer |
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Authors: | Hideo Inaji Chiyomi Egawa Yoshifumi Komoike Kazuyoshi Motomura Kinji Nishiyama Tatsuki R Kataoka Hiroki Koyama |
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Institution: | (1) Department of Breast Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital Organization, 1-3-3 Nakamichi, Higashinari-ku, Osaka 537-8511, Japan;(2) Department of Radiation Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital Organization, Osaka, Japan;(3) Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka Prefectural Hospital Organization, Osaka, Japan |
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Abstract: | Breast-conserving treatment is well established as a safe method of treatment for the majority of breast cancers. Issues to
be addressed concerning breast-conserving treatment include the omission of radiation therapy in low-risk patients, optimal
local and systemic treatment for ipsilateral breast tumor recurrence, classification of ipsilateral breast tumor recurrence
into true recurrences and new primary cancers, and the selection of patients who are eligible for breast conservation after
neoadjuvant chemotherapy. There is much evidence that sentinel node biopsy is an accurate method of screening for axillary
nodal status in patients with early breast cancer. Clearly, the avoidance of axillary dissection improves quality of life.
The feasibility, accuracy, and timing of sentinel node biopsy in patients undergoing neoadjuvant chemotherapy are not yet
clear. Also, the clinical significance of micrometastasis should be evaluated to determine the optimal application of sentinel
node biopsy. There is interest in replacing breast-conserving treatment by nonsurgical ablation, although additional findings
are needed to show that this technique is a true advance in breast cancer treatment. |
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Keywords: | Breast cancer Breast-conserving treatment Ipsilateral breast tumor recurrence Sentinel node biopsy Nonsurgical ablation |
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