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慢性肺源性心脏病患者红细胞免疫粘附功能的研究
引用本文:林彦,陈学魁,刘长庭,张进川.慢性肺源性心脏病患者红细胞免疫粘附功能的研究[J].军医进修学院学报,1999,20(4):286-287.
作者姓名:林彦  陈学魁  刘长庭  张进川
作者单位:1. 解放军总医院南楼一科,北京 100853
2. 白求恩医科大学二院呼吸内科,长春,130041
摘    要:目的:通过对肺心中层得红细胞免疫附功能进行研究,进一步探讨慢性肺源心脏病免疫调节机制。方法:检测27例心病患者外周血红细胞免疫复合物花环率(RICR)及细胞膜表面C3b受体花环率(RCR),上急发期患者21例,缓解期患者6例,并利用流式细胞术测定红细胞膜CD58表达。结果:肺心病组RCR在急发期及缓解工匀低于以对照组(P〈0.001,,P〈0.0001),急发期较缓期也有减低(P〈0.05)。急发

关 键 词:肺心病  红细胞免疫

Study on the erythrocyte adhesive function in patients with chronic pulmonary heart disease
Lin Yan,Chen Xuekui,Liu Changting,Zhang Jinchuan.Study on the erythrocyte adhesive function in patients with chronic pulmonary heart disease[J].Academic Journal of Pla Postgraduate Medical School,1999,20(4):286-287.
Authors:Lin Yan  Chen Xuekui  Liu Changting  Zhang Jinchuan
Abstract:Objective:The erythrocyte adhesive function in 27 patients with chronic pulmonary heart disease (CPHD) was observed. Methods:In total 27 CHPD patients, 21 were in acute attack stage and 6 in remission stage. The RICR, RCR and CD 58 were tested by flowcytometer. Results:(1) RCR level in CPHD was worse than those in the control. In acute attack cases, RCR level was the lowest. (2) RICR level of acute attack cases showed decreased. (3) CD 58 on membrane of erythrocyte expressed stronger in CPHD, neither did it improve in remission cases nor did it return to normal level. Conclusion:The erythrocyte adhesive function in patients with CPHD seems to be markedly disturbed. In order to prevent relapse, we should improve the immune ability of erythrocyte by treating the patients with CPHD.
Keywords:CD58
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