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慢性前列腺炎的病原菌及其耐药性研究
引用本文:王应芳,孟灵,徐雅萍,张润玲. 慢性前列腺炎的病原菌及其耐药性研究[J]. 中华医院感染学杂志, 2008, 18(12)
作者姓名:王应芳  孟灵  徐雅萍  张润玲
作者单位:1. 兰州大学第二医院检验科,甘肃,兰州,730030
2. 解放军总医院微生物科,北京,100853
摘    要:目的 了解慢性前列腺炎(CP)病原菌感染及其对常用抗菌药物的耐药性,对CP的诊断和治疗提供科学依据.方法 对143例CP患者的前列腺液进行常规病原菌培养和药物敏感性试验.结果 82例病原菌培养阳性,阳性率57.34%,共分离出病原菌85株,其中革兰阳性球菌73株,占85.9%,革兰阴性杆菌12株,占14.1%;革兰阳性球菌中以凝固酶阴性葡萄球菌(CNS)为主(60.0%),其次为金黄色葡萄球菌(12.9%)、肠球菌属(11.8%);CNS对常用的β-内酰胺类、喹诺酮类,红霉素、四环素类抗菌药物耐药率较高,对万古霉素、利福平、复方新诺明、庆大霉素较敏感.结论 慢性前列腺炎的病原菌感染以CNS为主,对CNS引起的CP,首选利福平、复方新诺明、庆大霉素;选择敏感且对前列腺组织渗透性强的药物是慢性前列腺炎抗菌治疗的关键.

关 键 词:慢性前列腺炎  病原菌  耐药性  凝固酶阴性葡萄球菌

Pathogens Causing Chronic Prostatitis and Their Resistance
WANG Ying-fang,MENG Ling,XU Ya-ping,ZHANG Run-ling. Pathogens Causing Chronic Prostatitis and Their Resistance[J]. Chinese Journal of Nosocomiology, 2008, 18(12)
Authors:WANG Ying-fang  MENG Ling  XU Ya-ping  ZHANG Run-ling
Affiliation:WANG Ying-fang*,MENG Ling,XU Ya-ping,ZHANG Run-ling(*The Second Hospital,Lanzhou University,Lanzhou,Gansu 730030,China)
Abstract:OBJECTIVE To comprehend the bacterial infection and resistance to antimicrobial agents of the pathogenic bacteria causing chronic prostatitis(CP),so as to provide scientific basis for the diagnosis and treatment of CP.METHODS Bacterial culture and antimicrobial agents sensitivity tests were applied to prostatic fluid in 143 patients with chronic prostatitis.RESULTS A total of 85 strains of bacteria were isolated from 143 clinical specimens and the positive rate was 57.34%.In these strains,Gram-positive cocc...
Keywords:Chronic prostatitis  Pathogenic bacteria  Drug resistance  Coagulase negative Staphylococcus  
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