| 内毒素诱导p38MAPK信号转导作用的研究进展 |
| |
| 引用本文： | 姚琳,余书勤,张锡然.内毒素诱导p38MAPK信号转导作用的研究进展[J].中国病理生理杂志,2004,20(12):2357-2362. |
| |
| 作者姓名： | 姚琳 余书勤 张锡然 |
| |
| 作者单位： | 南京师范大学生命科学学院，江苏 南京 210097 |
| |
| 摘 要： | The diseases caused by endotoxin have seriously affected human health. Previous studies have shown that p38 MAPK pathway is involved in the intracellular signal transduction induced by lipopolysaccharide (LPS), which plays an important role in the activation of inflammation-related cells to release inflammation mediator. Recently there have been some progresses in the isoforms distribution, substrate, molecular mechanism of regulating the release of inflammatory mediators, cellular specific activation and levels of p38 MAPK.
|
| 关 键 词： | 脂多糖 p38丝裂原活化蛋白激酶 炎性介质 信号转导 |
| 文章编号： | 1000-4718(2004)12-2357-06 |
| 收稿时间： | 2003-04-15 |
Recent progresses in endotoxin-induced p38 MAPK signal transduction |
| |
| YAO Lin,YU Shu-qin,ZHANG Xi-ran.Recent progresses in endotoxin-induced p38 MAPK signal transduction[J].Chinese Journal of Pathophysiology,2004,20(12):2357-2362. |
| |
| Authors: | YAO Lin YU Shu-qin ZHANG Xi-ran |
| |
| Institution: | College of Life Science, Nanjing Normal University, Nanjing 210097, China |
| |
| Abstract: | A Review The diseases caused by endotoxin have seriously affected human health. Previous studies have shown that p38 MAPK pathway is involved in the intracellular signal transduction induced by lipopolysaccharide (LPS), which plays an important role in the activation of inflammation-related cells to release inflammation mediator. Recently there have been some progresses in the isoforms distribution, substrate, molecular mechanism of regulating the release of inflammatory mediators, cellular specific activation and levels of p38 MAPK. |
| |
| Keywords: | Lipopolysaccharides Mitogen-activated protein kinase p38 Inflammation mediators Signal transduction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国病理生理杂志》浏览原始摘要信息 |
| 点击此处可从《中国病理生理杂志》下载免费的PDF全文 |
