消疲灵颗粒增强老年慢性肺心病患者免疫功能的临床研究

目的：采用开放对比研究消疲灵颗粒增强老年慢性肺心病患者免疫功能。方法：选择60岁以上老年慢性肺心病患者80例，随机分成两组，试验组应用对症及抗炎治疗外加消疲灵颗粒10g，口服，一日三次，14d为一疗程。对照组仅用对症及抗炎治疗。结果：显示免疫功能测定（CD3，CD4，CD4／CD8，NK细胞活性测定，IgG,IgA）,试验组治疗后明显上升与治疗前比较差异有显著性（P＜0．01），对照组无明显变化。结论：消疲灵颗粒具有肯定的免疫增强作用，是一种疗效良好、安全的免疫治疗和预防药物。

A clinical study of Xiaopiling grains in the improvement of chronic pulmonary heart disease in elder patients

OBJECTIVE To observe the improvement of immunity in elder patients of chronic pulmonary heart disease. METHOD 80 cases of chronic pulmonary heart disease patients beyond 60 years old were divided into two groups randomly. The control group were treated by antibiotic and symptom therapy. The experimental group were treated by Xiaopiling grains (10g.po.tid.14 d a course).RESULTS The efficiency rate for experimental group and control group were 77.5% and 67.5%. Immunity function (CD3, CD4, CD4/CD8, activit of NK,IgG,IgA) in experimental group were significantly improved compared with those indexes before the therapy ( P <0.01). but the changes were not found in control group.CONCLUSION Xiaopiling grains can improve the immunity.