| 川芎提取工艺的优化 |
| |
| 引用本文： | 白海波,王剑飞,宋子荣.川芎提取工艺的优化[J].中国实验方剂学杂志,2003,9(4):8-10. |
| |
| 作者姓名： | 白海波 王剑飞 宋子荣 |
| |
| 作者单位： | 海南养生堂药物研究中心,浙江,杭州,310007 |
| |
| 摘 要： | 目的：研究川芎中有效成分阿魏酸及藁本内酯的最佳提取条件。方法：以HPLC为含量测定方法，采用重复-正交实验法，以乙醇浓度(A)、溶剂量(B)、提取时间(C)和提取次数(D)4个因素，每个因素选取3个水平进行实验，经工艺验证，最后确定提取工艺。结果：因素A、D对阿魏酸的含量有显著影响。因素A、C、D对藁本内酯的含量有极显著影响。结论：80％乙醇10倍量，回流提取3次，每次1．0h为阿魏酸、藁本内酯较佳提取条件。
|
| 关 键 词： | 川芎 阿魏酸 藁本内酯 正交实验 HPLC |
| 文章编号： | 1005-9903(2003)04-0008-03 |
| 收稿时间： | 7/2/2002 12:00:00 AM |
Study on Optimizing the Extraction Process of Ferulic Acid and Ligustilide in Ligusticum Chuanxion Hort. |
| |
| BAI Hai-bo,WANG JIan-fei,SONG Zi-rong.Study on Optimizing the Extraction Process of Ferulic Acid and Ligustilide in Ligusticum Chuanxion Hort.[J].China Journal of Experimental Traditional Medical Formulae,2003,9(4):8-10. |
| |
| Authors: | BAI Hai-bo WANG JIan-fei SONG Zi-rong |
| |
| Institution: | Hainan Yangshengtang Medical Research Center,Hangzhou 310007,China |
| |
| Abstract: | Objective:To optimize the extraction process of Ferulic Acid and Ligustilide in Ligusticum chuanxiong Hort.Method:The optimum extraction was investigated by the orthogonal design,Ferulic Acid and Ligustilide determined by HPLC,the concentration of ethanol,amount of ethanol,extraction time and extraction times were the four factors in the experiment.Results:The optimum extraction process was adding 10 times amount of 80% alcohol,refluxing and extraction for 3 times,1h each time.Conclution:This extraction process shows higher yield of Ferulic acid and ligustilide and is available for industrial production. |
| |
| Keywords: | Orthogonal design Ferulic Acid Ligusticum chuanxiong Hort extraction process HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
