Efficacy of benzoxazinorifamycins in a mouse model of Chlamydia pneumoniae lung infection |
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| Authors: | Campbell Lee Ann Kuo Cho-Chou Suchland Robert J Rothstein David M |
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| Institution: | Department of Pathobiology, University of Washington, Seattle, Washington 98195, USA. |
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| Abstract: | The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight. |
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