肠内营养混悬液对急性脑出血并吞咽障碍患者营养状况及感染的影响研究

目的探讨肠内营养混悬液对急性脑出血并吞咽障碍患者营养状况及感染的影响。方法选择深圳市宝安区第二人民医院2013年2月—2014年2月收治的急性脑出血并吞咽障碍患者78例,按照随机、平行、对照原则分为对照组和观察组,每组39例。对照组患者在常规治疗基础上给予家属自制的普通流质饮食,观察组患者在常规治疗基础上给予肠内营养混悬液。观察两组患者治疗6周后营养状况、治疗前和治疗6周后营养相关指标〔血清血红蛋白(Hb)、清蛋白(ALB)、免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM)水平〕及住院期间感染情况。结果观察组患者治疗后营养状况优于对照组,且营养低下者严重程度轻于对照组(P0.05)。两组患者治疗前血清Hb、ALB、IgG、IgA、IgM水平比较,差异均无统计学意义(P0.05);观察组患者治疗后血清Hb、ALB、IgG、IgA、Ig M水平均高于对照组(P0.05)。观察组患者住院期间感染率为38.5%,低于对照组的66.7%(P0.05)。结论肠内营养混悬液可较好地改善急性脑出血并吞咽障碍患者营养状况,减轻营养低下严重程度,提高免疫力,减少住院期间感染的发生。

Impact of Enteral Nutrition Suspension on Nutritional Status and Infection in Acute Cerebral Hemorrhage Patients Com- plicated with Dysphagia

Objective To investigate the impact of enteral nutrition suspension on nutritional status and infection in a- cute cerebral hemorrhage patients complicated with dysphagia. Methods From February 2013 to February 2014,78 acute cere- bral hemorrhage patients complicated with dysphagia were selected in the Second People＆#39;s Hospital of Baoan District,Shenz- hen. According to random,parallel,control principle,all patients were divided into control group and observation group,each of 39 cases. Based on conventional therapy,control group given self - made ordinary liquid diet,observation group given enteral nutrition suspension. Nutritional status after 6 weeks of treatment,nutrition index（including serum levels of Hb,ALB,IgG, IgA,IgM）before treatment and after 6 weeks of treatment,and incidence of infection during hospitalization between the two groups were compared. Results Nutritional status of observation group after 6 weeks of treatment was better than that of control group,and severity of poor nutrition was slighter than that of control group（P 〈 0. 05）. No significant differences was found in serum levels of Hb,ALB,IgG,IgA,IgM between the two groups before treatment（ P 〉 0. 05）,while serum levels of Hb, ALB,IgG,IgA,IgM of observation group after 6 weeks of treatment were higher than those of control group（P 〈 0. 05）. The incidence of infection of observation group during hospitalization was 38. 5% ,was lower than that of observation group（ P 〈0. 05）. Conclusion Enteral nutrition suspension can certainly improve the nutritional status and immunity of acute cerebral hemorrhage patients complicated with dysphagia,reduce the severity of poor nutrition and incidence of infection during hospitali- zation.