| 极低出生体重儿转归因素分析及肺表面活性剂的作用 |
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| 引用本文： | 王建辉,余加林. 极低出生体重儿转归因素分析及肺表面活性剂的作用[J]. 儿科药学杂志, 2009, 15(4): 19-21 |
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| 作者姓名： | 王建辉 余加林 |
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| 作者单位： | 重庆医科大学附属儿童医院,重庆,400014;重庆医科大学附属儿童医院,重庆,400014 |
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| 摘 要： | 目的:探讨影响极低出生体重儿(VLBWI)转归的相关因素及肺表面活性剂(PS)在其中的作用.方法:将305例VLBWI分别按出生体重和住院年份分组,对其临床资料进行回顾性分析.结果:所有住院惠儿均有一种及以上的并发症,最常见的为病理性黄疸(53.4%)、酸中毒(43.3%)、呼吸暂停(33.3%)、新生儿硬肿症(32.1%).本组总体院内病死率为3.0%,其中出生体重≤1 000 g组、～1 250 g组及～1 500 g组分别为12.0%、3.3%和1.6%,组间比较差异有统计学意义(P<0.05).前三年后四年两个时间段比较.病死率差异无统计学意义(P>0.05).导致VLBWI死亡的主要原因为新生儿呼吸窘迫综合征(66.6%):使用PS组治疗NRDS治愈率显著高于未使用PS组(61.5%比21.7%,P<0.05).结论:体重、严重新生儿并发症是影响VLBWI转归的重要因素;NRDS是致VLBWI死亡的最主要原因;应用PS可以明显提高临床NRDS的治愈率.
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| 关 键 词： | 极低出生体重儿 住院病死率 呼吸窘迫综合征 肺表面活性剂 |
Constitution of the Complications of Very Low Birth Weight Infants and Analysis of Factors Related to the Outcome |
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| WANG Jian-hui,YU Jia-lin. Constitution of the Complications of Very Low Birth Weight Infants and Analysis of Factors Related to the Outcome[J]. Journal of Pediatric Pharmacy, 2009, 15(4): 19-21 |
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| Authors: | WANG Jian-hui YU Jia-lin |
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| Affiliation: | WANG Jian-hui,YU Jia-lin(The Children's Hospital of Chongqing Medical University,Chongqing 400014,China) |
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| Abstract: | Objective:To investigate the constitution of the complications and the factors in relation to improving outcome of very low birth weight infants(VLBWI).Methods:The clinic data of 305 VLBWI during the past 8 years was analyzed retrospectively by dividing patients into three groups according to the birth weight,and into two groups according to the admitting chronology.Results:All hospitalized VLBWI had at least one complication,and the most common were pathologic jaundice(163 cases,53.4%),acidosis(132 cases,4... |
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| Keywords: | Very low birth weight infants Hospital mortality Respiratory distress syndrome Pulmonary surfactant |
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