| 重组人表皮生长因子凝胶治疗肿瘤患者口腔溃疡临床研究 |
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| 引用本文： | 朱述琳,薛现霞,侯栋梁.重组人表皮生长因子凝胶治疗肿瘤患者口腔溃疡临床研究[J].齐鲁护理杂志,2005(6). |
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| 作者姓名： | 朱述琳 薛现霞 侯栋梁 |
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| 作者单位： | 滕州市中心人民医院，滕州市中心人民医院，山东省肿瘤防治研究院 山东滕州277500，山东滕州277500 |
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| 摘 要： | 目的:观察重组人表皮生长因子(rhEGF)凝胶对肿瘤患者放化疗后并发口腔溃疡的疗效。方法:随机将214例肿瘤放化疗后并发口腔溃疡患者进行分组,治疗组116例rhEGF凝胶治疗,对照组98例0.5%碘伏液治疗,两组对照观察。结果:治疗组显效102例,有效14例,总有效率100%;对照组98例,显效42例,有效36例,无效20例,总有效率79.6%,两组有显著性差异(P<0.01)。结论:rhEGF凝胶对口腔溃疡创面具有明显促进愈合作用。
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| 关 键 词： | 重组 人表皮生长因子 药物治疗 放射治疗 口腔溃疡 |
Clinical study on recombinant human epidermal growth factor gel in the treatment of oral ulcer induced by chemotherapy and radiotherapy. |
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| Zhu Shulin,Xue Xianxia,Hou Dongliang.Clinical study on recombinant human epidermal growth factor gel in the treatment of oral ulcer induced by chemotherapy and radiotherapy.[J].Journal of Qilu Nursing,2005(6). |
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| Authors: | Zhu Shulin Xue Xianxia Hou Dongliang |
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| Abstract: | Objective: To investigate the effect of recombinant human epid er mal growth factor gel (rhEGF) on oral ulcer induced by chemotherapy and radiothe rapy. Methods: 214 patients were randomly divided into test group (n=116) receiv ing rhEGF gel and control group (n=98) receiving iodine. Results: The effective rate in test group was 100%, much higher than in control group (79.6%, P<0 .01). Conclusion: rhEGF gel can promote healing of oral ulcer induced by c hemotherapy and radiotherapy. |
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| Keywords: | Recombinant human epidermal growth factor Drug therapy Radiotherapy Oral ulcer |
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