| 天蓝淡红链霉菌SIPI 1482及其突变株的研究：I.发酵过程中 … |
| |
| 引用本文： | 钱秀萍,倪兵.天蓝淡红链霉菌SIPI 1482及其突变株的研究：I.发酵过程中 …[J].中国医药工业杂志,2000,31(5):200-203. |
| |
| 作者姓名： | 钱秀萍 倪兵 |
| |
| 作者单位： | [1]上海医药工业研究院 [2]华东师范大学电镜中心 |
| |
| 摘 要： | 用光学显微镜和透射电子显微镜，研究天蓝淡红链霉素ＳＩＰＩ １４８２及其突变株ＳＩＰＩ １４８２－ＮＳ－４在发酵过程中细胞形态和超微结构的变化。发现两者最大的不同在于：亲株能合成柔红霉素，产抗期细胞内含物丰富，但脂肪颗粒较少；突变株不能合成柔红霉素，细胞中含有丰富的脂肪颗粒。由于柔红霉素的生物合成与脂肪酸的合成密切相关，提示超微结构中脂肪颗粒的变化可能与柔红霉素的合成有关。
|
| 关 键 词： | 柔红霉素 细胞结构 天蓝淡红链霉素 发酵 |
| 修稿时间： | 1999-06-25 |
Changes of Cellular Morphology and Structure of Streptomyces coeruleorubidus SIPI 1482 and Its Mutant in Fermentation Process |
| |
| Authors: | QIAN Xiu Ping NI Bing XU Wen Si CHEN Dai Jie |
| |
| Institution: | QIAN Xiu Ping 1,NI Bing 2,XU Wen Si 1,CHEN Dai Jie 1 |
| |
| Abstract: | The changes of cellular morphology and ultrastructure of Streptomyces coeruleorubidus SIPI 1482 and its mutant SIPI 1482 NS 4 in fermentation process were observed with light microscope and electron microscope.The differences were found that the parent which could biosynthesize daunomycin had more cellular contents and little fatty granules,but there was a variety of fatty granules in the mutant which could not produce daunomycin.It implied that there was a relationship between the changes of fatty granules and the production of daunomycin. |
| |
| Keywords: | Streptomyces coeruleorubidus daunomycin morphology structure |
| 本文献已被 CNKI 维普 等数据库收录！ |
